Progress in cell cultures using for preparation of influenza vaccines

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Abstract

The review presents the literature data concerning successful using of primary and continuous cell cultures (instead of embryonated eggs) as substrates for production of inactivated and live influenza vaccines. The possibilities of wide-scale production of influenza vaccines on the basis of certificated continuous mammalian cell lines - Vero, PEP.C6 and MDCK are analyzed.

About the authors

О. К. Kuznetsov

Research Institute of Influenza of the RAMS

Author for correspondence.
Email: medaj@eco-vector.com
Russian Federation, St. Petersburg

A. I. Migunov

Research Institute of Influenza of the RAMS

Email: medaj@eco-vector.com
Russian Federation, St. Petersburg

Yu. R. Romanova

Institute of Applied Microbiology

Email: medaj@eco-vector.com
Austria

A. Yu. Egorov

Institute of Applied Microbiology

Email: medaj@eco-vector.com
Austria

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