Needle aspiration biopsy in diagnostics of thyroid nodules

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Abstract

In this article results of thick needle aspiration biopsy of thyroid nodules done in 5463 patients are presented. In 4450 (58 %) cases according to the given cytological diagnosis benign forms of thyroid pathology were found. 212 (4 %) cases had cytological presentations of malignancy while in 428 (8 %) cases cytological diagnosis could not rule out presence of malignancy. In 373 (7 %) cases results of primary puncture biopsy were non-informative. 761 patients underwent operative treatment. Comparing the received cytological and histological investigations, the following results were obtained: sensitivity 81,4, specificity 83,6, false positive 6,6 and false negative 16,3.

About the authors

A. S. Kuzmichov

Medical Academy of Postgraduate Studies

Author for correspondence.
Email: medaj@eco-vector.com
Russian Federation, St. Petersburg

References

  1. Bahos R., Selvaggi S. V., De Jong S. et al. Fineneedle aspiration of the thyroid. Rate and causes of cytohistopathologic discaordance // Diagnostic Cytopathology. 2000. Vol. 23. № 4. p. 233-237.
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  5. Gharib H. Changing concepts in the diagnosis and management of thyroid nodules // Endocrinol, and Metabol. Clin. North Am. 1997. Vol 26. № 4. p. 777-800.

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