He-Ne Laser- induced changes of potassium ion currents in neurons of Lymnaea stagnalis

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Abstract

The influence of He-Ne laser 632,8 nm on voltage-gated potassium currents had been studied on the model of isolated neurons from Lymnaea stagnalis using the clamp technique with intracellular dialyze. The red light doses ranged from 0,7×10-4J to 0,7×10-3J and intensity was 1,5×10-2 W/m2 . The resulted revealed the dependence of postirradiation changes of ion currents amplitude on light dose and neuron’s initial functional state. It had been found that the processes of ion currents inactivation proceeded at a much faster rate as well as slower rate. This phenomenon was dependent on type of potassium channels of neuron membrane.

About the authors

M. E. Kolpakova

I. P. Pavlov State Medical University

Author for correspondence.
Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg, 197022

A. I. Vislobokov

I. P. Pavlov State Medical University

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg, 197022

T. D. Vlasov

I. P. Pavlov State Medical University

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg, 197022

N. N. Petrishchev

I. P. Pavlov State Medical University

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg, 197022

Ju. D. Ignatov

I. P. Pavlov State Medical University

Email: shabanov@mail.rcom.ru

Академик РАМН

Russian Federation, St. Petersburg, 197022

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