Significance of detecting antithyroid antibodies in patients with newly diagnosed toxic goiter

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Abstract

The paper represents the results of dynamic investigation of the levels of antithyroid antibodies in female cases of untreated Graves’ disease: the high level of autoantibodies to thyroid-stimulating hormone receptor found by prior examination and the lack of any decrease in the level of this autoantibodies during treatment indicates a high risk of acute condition following thyrostatic therapy.

About the authors

N. A. Garbuz

All-Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

Author for correspondence.
Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg

N. A. Sokolan

All-Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg

N. A. Altukhova

All-Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg

L. В. Drigina

All-Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg

N. М. Kalinina

All-Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg

References

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  5. Maugendre D., Massart C. Clinical value of a new TSH binding inhibitory activity assay using human TSH receptors in the follow-up of antithyroid drug treated Graves’ disease. Comparison with thyroid stimulating antibodie bioassay // Clin. Endocrinol. 2001. Vol. 54. № 1. P. 89-96.
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  7. Vanderpump M. P. Tunbridge W. M.. French J. M. et al. Incidence of thyroid disorfers in the community: a twenty-year follow-up of the Whickham Survey И Clin. Endocrinol. 1995. Vol. 43. P. 55-68.
  8. Volpe’ R. B-lymphocytes in autoimmune thyroid disease (AITD) // Rev. in Endocrine @ Metabolic. Disorders. 2000. Vol. 1. P. 79-86.

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