Apoptosis in normal and pathological conditions

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Abstract

Apoptosis is a physiological, actively regulated cell death. Its biological role is outstandingly important, since it serves as defense mechanism aimed to eliminate from the body useless or potentially dangerous cells, and functions in tight balance with proliferation and differentiation processes. Research on programmed cell death has become a very active area in modern biology. Besides a visible fundamental impact into the understanding of mechanisms of cellular homeostasis, studies on apoptosis are gaining an increasing significance for the applied medical science.

About the authors

M. Yu. Grigoriev

N. N. Petrov Institute of Oncology

Author for correspondence.
Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg

E. N. Imyanitov

N. N. Petrov Institute of Oncology

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg

K. P. Hanson

N. N. Petrov Institute of Oncology

Email: shabanov@mail.rcom.ru

член-корреспондент РАМН

Russian Federation, St. Petersburg

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