Analysis of contemporary stomach cancer pathomorphosis on population level

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Abstract

Here we have performed a comparative population analysis of the most important epidemiological and clinical- morphological indicators of stomach cancer (SC) pathogenesis. SC is one of the most frequent forms of malignant growth that have an impact on the current demographic situation. A profound study of the contemporary SC pathomorphosis features based on the data of St Petersburg Cancer Registry from 1994-2005 has confirmed the actuality of the problem, defined by the high incidence of the disease and late diagnostics at the generalization stage. Risk groups have been revealed, as well as the frequency of different histological forms of SC and their correlation with one-year survival of the patients. Moreover, we have determined the deficits in morphological diagnostics of SC at the hospital stage, the objective causes of these deficits and possibilities of rational improvement. The results of this work should be helpful in optimizing individual as well as group prognosis of the disease. Our data confirm the necessity of developing and introducing prophylactic screening programs as the only method of detecting early preclinical SC and reducing the incidence of advanced SC.

About the authors

I. A. Danilova

St. Petersburg Mechnikov State Medical Academy; N. N. Petrov Institute of Oncology; Population Cancer Register

Author for correspondence.
Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg

V. М. Merabishvili

St. Petersburg Mechnikov State Medical Academy; N. N. Petrov Institute of Oncology; Population Cancer Register

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg

N. М. Anichkov

St. Petersburg Mechnikov State Medical Academy; N. N. Petrov Institute of Oncology; Population Cancer Register

Email: shabanov@mail.rcom.ru

член-корреспондент РАМН

Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg

О. F. Chepick

St. Petersburg Mechnikov State Medical Academy; N. N. Petrov Institute of Oncology; Population Cancer Register

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg

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