Directions in diagnostics of gastric malt lymphoma



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Abstract

In review, recent data displayed regarding the state of ML-diagnostics in gastric area and possible next day-steps for improving the level of detection of the pathological changes. Possible association of ML detection with importance of early diagnostics of developing gastric cancer and noncancerous diseases is also discussed.

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About the authors

V P Kalinovsky

Prof. N. N. Petrov Research Institute of Oncology, St. Petersburg

A R Shumakov

Prof. N. N. Petrov Research Institute of Oncology, St. Petersburg

E I Tkachenko

Email: info@gastrofarm.ru

J A Limareva

References

  1. Аруин Л.И., Капуллер Л.Л., Исаков В.А. Морфологическая диагностика болезней желудка и кишечника. М., 1998. 483 с.
  2. Гершанович М.Л., Калиновский В.П., Никитина М.В. и др. Новый метод лечения мальт-лимфом желудка // Вопр. онкол. 2010. Т. 25. С. 5-15.
  3. Калиновский В.П., Овсянников А.И., Успенская М.Н. и др. Разработка и применение метода количественного определения уреазы на планшетах у больных с хроническими заболеваниями желудка, ассоциированными с Helicobacter pylori // Гастроэнтерология Санкт-Петербурга. 2005. № 3-4. С. 50-53.
  4. Калиновский В.П., Щербаков А.М., Овсянников А.И. и др. Malt-лимфома желудка: биохимические, эндоскопические и морфологические критерии регрессии опухоли при комплексной химиотерапии: Пособие для врачей. СПб., 2011. 24 с.
  5. Новик A.A., Данилова И.А., Антонова И.В., Денисов Н.Л. Морфо-эпидемиологическое исследование MALT-лимфом желудка // Рос. журн. гастроэнтерол., гепатол., колопроктол. 1999. T. IX. № 5. Прил. 8. А126.
  6. Ashton-Key М., Biddolph S.C., Stein H. et al. Heterogeneity of bcl-2 expression in MALT lymphoma // Histopathology. 1995. Vol. 26. P. 75-78.
  7. Bacon C.M., Du M.Q., Dogan A. Mucosa-associated lymphoid tissue (MALT) lymphoma: a practical guide for pathologists// J. Clin. Pathol. 2007. Vol. 60. P. 361-372.
  8. Begum S., Sano T., Endo H. et al. Mucosal change of the stomach with low-grade mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori: follow-up study of 48 cases // J. Med. Invest. 2000. Vol. 47. P. 36-46.
  9. Bende R.J., van Maldegem F., van Noesel C.J. Chronic inflammatory disease, lymphoid tissue neogenesis and extranodal marginal zone В-cell lymphomas // Haematologica. 2009. Vol. 94 (8). P. 1109-1123.
  10. Bishton М., Kencaly М., Johnstone R. et al. Epigenetic targets in hematological malignancies: combination therapies with HDACis and demethylating agents // Expert. Rev. Anticancer Ther. 2007. Vol. 7. P 1439- 1449.
  11. Brisslert M., Enarsson K., Lundin S. et al. Helicobacter pylori induce neutrophil transcndothelial migration: role of the bacterial HP-NAP // FEMS Microbiol. Lett. 2005. Vol. 249. P. 95-103.
  12. Cabral M.M., Mendes C.M., Castro L.P. et al. Apoptosis in Helicobacter pylori gastritis is related to cagA status // Helicobacter. 2006. Vol. 11. P. 469-476.
  13. Cohen S.M., Petryk M., Varma M. et al. Non-Hodgkin’s Lymphoma of Mucosa-Associated Lymphoid Tissue//Oncologist. 2006. Vol. 11. P. 1100-1117.
  14. Copie-Bergman C., Locher C., Levy M. et al. Metachronous gastric MALT lymphoma and early gastric cancer: is residual lymphoma a risk factor for the development of gastric carcinoma? //Ann. Oncol. 2005. Vol. 16. P. 1232-1236.
  15. D’Elios M.M., Amedei A., Cappon A. et al. The neutrophil-activating protein of Helicobacter pylori (HP-NAP) as an immune modulating agent // FEMS Immunol. Med. Microbiol. 2007. Vol. 50. P. 157-164.
  16. Du MQ. Molecular biology of gastric MALT lymphoma: application in clinical management // Hematology. 2002. Vol. 7. P. 339-344.
  17. Dundon W.G., Nishioka H., Polenghi A. et al. The neutrophil-activating protein of Helicobacter pylori // Int. J. Med. Microbiol. 2002. Vol. 291. P. 545-550.
  18. El-Zimaity H.M., El-Zaatari F.A., Dore M.P. et al. The differential diagnosis of early gastric mucosa-associated lymphoma: polymerase chain reaction and paraffin section immunophenotyping // Mod. Pathol. 1999. Vol. 12. P. 885-893.
  19. Ernst P. Review article: the role of inflammation in the pathogenesis of gastric cancer // Aliment Pharmacol. Ther. 1999. Suppl. 1. P. 13-18.
  20. Fischbach W., Goebeler M.E., Ruskone-Fourmestraux A. et al. Most patients with minimal histological residuals of gastric MALT lymphoma after successful eradication of Helicobacter pylori can be managed safely by a watch and wait strategy: experience from a large international series// Gut. 2007. Vol. 56. P. 1685-1687.
  21. Go J.H. Methylation analysis of cyclin-dependent kinase inhibitor genes in primary gastrointestinal lymphomas // Mod. Pathol. 2003. Vol. 16. P. 752-755.
  22. Go M.F., Chan K.Y., Versalovic J. et al. Cluster analysis of Helicobacter pylori genomic DNA fingerprints suggests gastroduodenal disease-specific associations // Scand. J. Gastroenterol. 1995. Vol. 7. P. 640-646.
  23. Hatz R.A., Meimarakis G., Lehn N. et al. Granulocyte activation by Helicobacter pylori // Eur. J. Med. Res. 1996. Vol. 1. P. 537-542.
  24. Herranz M., Esteller M. New therapeutic targets in cancer: the epigenetic connection // Clin. Transi. Oncol. 2006. Vol. 8. P. 242-249.
  25. Herranz M., Esteller M. DNA methylation and histone modifications in patients with cancer: potential prognostic and therapeutic targets // Methods Mol. Biol. 2007. Vol. 361. P. 25-62.
  26. Hosokawa Y. Anti-apoptotic action of API2-MALT1 fusion protein involved in t( 11; 18)(q21;q21 ) MALT lymphoma //Apoptosis. 2005. Vol. 10. P. 25-34.
  27. Hosokawa Y., Seto M. Nuclear factor kappaB activation and antiapoptosis in mucosa-associated lymphoid tissue lymphoma // Int. J. Hematol. 2004. Vol. 3. P. 215-223.
  28. Hosokawa Y., Suzuki H., Suzuki Y. et al. Antiapoptotic function of apoptosis inhibitor 2-MALT 1 fusion protein involved in t( 11; 18)(q21;q21 ) mucosa-associated lymphoid tissue lymphoma // Cancer Res. 2004. Vol. 64. P. 3452-3457.
  29. Huang Q., Ai L., Zhang Z.Y., Fan C.Y., Weiss L.M. Promoter hypermethylation and protein expression of the p16 gene: analysis of 43 cases of В-cell primary gastric lymphomas from China // Mod. Pathol. 2004. Vol. 17. P. 416-422.
  30. Isaacson P.G. Recent developments in our understanding of gastric lymphomas // Am. J. Surg. Pathol. 1996. Suppl. l.P. Sl-7.
  31. Isaacson P.G., Du M.Q. Gastric lymphomas: genetics and resistance to H. pylori eradication // Verh. Dtsch. Ges. Pathol. 2003. Vol. 87. P. 116-122.
  32. Isaacson P.G., Du M.Q. Gastrointestinal lymphoma: where morphology meets molecular biology // J. Pathol. 2005. Vol. 205. P. 255-274.
  33. Isaakson P., Wright D. Malygnant lymphoma of mucosa-associated lymphoid tissue: a distinctive В-cell lymphoma//Cancer. 1983. Vol. 52. P. 1410-1416.
  34. Konturek P.C., Konturek S.J., Brzozowski T. Helicobacter pylori infection in gastric carcinogenesis // J. Physiol. Pharmacol. 2009. Vol. 60. P. 3-21.
  35. Konturek P.C., Konturek S.J., Pierzchalski P. et al. Cancerogenesis in Helicobacter pylori infected stomachrole of growth factors, apoptosis and cyclooxygenases // Med. Sei. Monit. 2001. Vol. 7. P. 1092-1107.
  36. Leite K.R., Darini E., Canavez F.C. et al. Helicobacter pylori and cagA gene detected by polymerase chain reaction in gastric biopsies: correlation with histological findings, proliferation and apoptosis // Sao Paulo Med. J. 2005. Vol. 123. P. 113-118.
  37. Li Z., Wang H., Xue L. et al. Emu-BCL10 mice exhibit constitutive activation of both canonical and non-canonical NF-kappaB pathways generating marginal zone (MZ) В-cell expansion as a precursor to splenic MZ lymphoma // Blood. 2009. Vol. 114. P. 4158-4168.
  38. Lin W.C., Tsai H.F., Kuo S.H. et al. Translocation of Helicobacter pylori CagA into Human В lymphocytes,the origin of mucosa-associated lymphoid tissue lymphoma //Cancer Res. 2010. Vol. 70. P. 5740-5748.
  39. Lucas P.C., Yonczumi M., Inohara N. et al. Bel10 and MALT1. independent targets of chromosomal translocation in mall lymphoma, cooperate in a novel NF-kappa В signaling pathway // J. Biol. Client. 2001. Vol. 276. P. 19012-19019
  40. Martincz-Delgado B., Fernandez-Piqueras J., Garcia M.J. et al. Hypermethylation of a 5 CpG island of p16 is a frequent event in non-Hodgkin's lymphoma // Leukemia. 1997. Vol. 11. P. 425-428.
  41. Miehlke S., Genta R.M., Graham D.Y., Go M.F. Molecular relationships of Helicobacter pylori strains in a family with gastroduodenal disease //Am. J. Gastroenterol. 1999. Vol. 2. P. 364-368.
  42. Montalban C., Santon A., Redondo С. et al. Long-term persistence of molecular disease after histological remission in low-grade gastric MALT lymphoma treated with H. pylori eradication. Lack of association with translocation t( 11 ; 18): a 10-ycar updated follow-up of a prospective study // Ann. Oncol. 2005. Vol. 16 (9). P. 1539-1544.
  43. Morgner A., Bayerdörffer E., Neubauer A., Stolte M. Malignant tumors of the stomach. Gastric mucosa-associated lymphoid tissue lymphoma and Helicobacter pylori // Gastroenterol. Clin. North. Am. 2000. Vol. 29. P. 593-607.
  44. Muntean A.G., Hess J.L. Epigenetic dysregulation in cancer// Am. J. Pathol. 2009. Vol. 175. P. 1353- 1361.
  45. Nakagawa M., Seto M., Hosokawa Y. Molecular pathogenesis of MALT lymphoma: two signaling pathways underlying the antiapoptotic effect of API2-MALT1 fusion protein // Leukemia. 2006. Vol. 20. P. 929-936.
  46. Nakamura S., Aoyagi K., Iwanaga S. et al. Synchronous and metachronous primary gastric lymphoma and adenocarcinoma: a clinicopathological study of 12 patients // Cancer. 1997. Vol. 79. P. 1077-1085.
  47. Nakamura T., Inagaki H., Seto M. Nakamura S. Gastric low-grade В-cell MALT lymphoma: treatment, response, and genetic alteration 4 J. Gastroenterol. 2003. Vol. 10. P. 921-929.
  48. Nardone G., Staibano S., Rocco A. et al. Effect of Helicobacter pylori infection and its eradication on cell proliferation, DNA status, and oncogene expression in patients with chronic gastritis // Gut. 1999. Vol. 44. P. 789-799.
  49. Omonishi K., Yoshino T., Sakuma I. et al. bcl-6 protein is identified in high-grade but not low-grade mucosa-associated lymphoid tissue lymphomas of the stomach //ModPathol. 1998. Vol. 11. P. 181-185.
  50. Psyrri A., Papageorgiou S., Economopoulos T. Primary extranodal lymphomas of stomach: clinical presentation, diagnostic pitfalls and management // Ann. Oncol. 2008. Vol. 19. P. 1992-1999.
  51. Raderer M., Püspök A., Stummvoll G., Längle F., Chott A. Early cancer of the stomach arising after successful treatment of gastric MALT lymphoma in patients with autoimmune disease // Scand. J. Gastroenterol. 2003. Vol. 38. P. 294-297.
  52. Raderer M., Wöhrer S., Streubel B. et al. Assessment of disease dissemination in gastric compared with extragastric mucosa-associated lymphoid tissue lymphoma using extensive staging: a single-center experience //J.CIin. Oncol. 2006. Vol. 24. P. 3136-3141.
  53. Rokkas T., Ladas S., Liatsos C. et al. Relationship of Helicobacter pylori CagA status to gastric cell proliferation and apoptosis // Dig. Dis. Sci. 1999. Vol. 44. P. 487-493.
  54. Ruskoné-Fourmestraux A., Lavergne A., Aegerter P.H. et al. Predictive factors for regression of gastric MALT lymphoma after anti-Helicobacter pylori treatment // Gut. 2001. Vol. 48. P. 297-303.
  55. Siakantaris M.P., Pangalis G.A., Dimitriadou E. et al. Early-stage gastric MALT lymphoma: is it a truly localized disease? // Oncologist. 2009. Vol. 14. P. 148-154.
  56. Stathis A., Chini C., Bertoni F. et al. Long-term outcome following Helicobacter pylori eradication in a retrospective study of 105 patients with localized gastric marginal zone В-cell lymphoma of MALT type // Ann. Oncol. 2009. Vol. 20. P. 1086-1093.
  57. Sumida T., Kitadai Y., Hiyama T. et al. Antibodies to Helicobacter pylori and CagA protein arc associated with the response to antibacterial therapy in patients with H. pylori-positive API2-MALT1-negative gastric MALT lymphoma // Cancer Sei. 2009. Vol. 100. P. 1075-1081.
  58. Suzuki H., Saito Y., and Hibi T. Helicobacter pylori and Gastric Mucosa-associated Lymphoid Tissue (MALT) Lymphoma: Updated Review of Clinical Outcomes and the Molecular Pathogenesis // Gut and Liver. 2009. Vol. 3. P. 81-87.
  59. Thiberge J.M., Boursaux-Eudc C., Lehours P. et al. From array-based hybridization of Helicobacter pylori isolates to the complete genome sequence of an isolate associated with MALT lymphoma h BMC Genomics. 2010. Vol. 11. P. 368.
  60. Toyota M., Itoh F., Imai K. Can DNA methylation be a molecular marker for eradication of Helicobacter pylori in MALT lymphoma? 4 J. Gastroenterol. 2002. Vol. 37. P. 73-74.
  61. Umehara S., Higashi H., Ohnishi N., Asaka M., Hatakeyama M. Effects of Helicobacter pylori CagA protein on the growth and survival of В lymphocytes, the origin of MALT lymphoma // Oncogene. 2003. Vol. 22. P. 8337- 8342.
  62. Urakami Y., Sano T., Begum S. et al. Endoscopic characteristics of low-grade gastric mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori // J. Gastroenterol. Hepatol. 2000. Vol. 15. P. 113-119.
  63. Venizelos I., Tamiolakis D., Bolioti S., Nikolaidou S. Primary MALT lymphomas of the stomach: a pathological study of 18 cases // Rev. Esp. Enferm. Dig. 2007. Vol. 99. P 270-274.
  64. Vinatzer U., Gollinger M., Müllauer L., Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3 // Clin. Cancer Res. 2008. Vol. 14. P 6426-6431.
  65. Walduck A.K., Weber M., Wunder С. et al. Identification of novel cyclooxygenase-2-dcpendent genes in Helicobacter pylori infection in vivo // Mol. Cancer. 2009. Vol. 8. P 22.
  66. Wiindisch T., Kim T.D., Thiede С. et al. Etiology and therapy of Helicobacter pylori-associated gastric lymphomas // Ann. Hematol. 2003. Vol. 82. P. 535-545.
  67. Xia H.H., Talley N.J. Apoptosis in gastric epithelium induced by Helicobacter pylori infection: implications in gastric carcinogenesis // Am. J. Gastroenterol. 2001. Vol. 96. P. 16-26.

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Copyright (c) 2011 Kalinovsky V.P., Shumakov A.R., Tkachenko E.I., Limareva J.A.

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