The characteristics of metabolic blood cell response to viral infections of various etiology

We have found that the response of POL processes and a number of membrane values, to a viral attack is dependent on the biolodgical characteristics of the pathogene including the presense of lipid viral envelope, the peculiarities of viral multiplication and the release of newly synthetized viral particles from aggested cells of the host (gemmation together with a part of cellular membrane, host cell, lysis, etc.). The reaction of cyclic nucleotide system to the DNAand RNA-containing viruses is shown to be different which is likely to be explained by the peculiarities of the viral multiplication in the injrured cells of the microorganism as well as the necessity of IKK protective factors production (e.g., lymphokines including interferon and immunoglobulins).

acute respiratory viral infection, free-radical oxidation, hormones, cyclic nucleotides, phospholipids, membrane enzymes