Тиреотропный гормон как нейрогормон и нейромодулятор

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Аннотация

В обзоре освещаются вопросы экспрессии биологически активного тиреотропного гормона (ТТГ), его ос- и Р-субъединиц. Рассматривается структура, локализация и регуляция экспрессии мРНК ос- и р- субъединиц ТТГ. Уделено внимание распределению ТТГ в пределах ЦНС, а также гормональной и нейромедиаторной регуляции секреции и биосинтеза ТТГ и мРНК его субъединиц. Кроме того, по­дробно описана структура рецепторов ТТГ, их экспрессия, локализация и регуляция.

Об авторах

Н. С. Сапронов

Научно-исследовательский институт экспериментальной медицины РАМН

Автор, ответственный за переписку.
Email: shabanov@mail.rcom.ru

член-корреспондент РАМН

Россия, Санкт-Петербург

Ю. О. Федотова

Научно-исследовательский институт экспериментальной медицины РАМН

Email: shabanov@mail.rcom.ru
Россия, Санкт-Петербург

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