Immunocytochemical study of Helicobacter pylori in oral, stomach and rectum mucosa



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Abstract

Helicobacter pylori (HP) was verified in human stomach (antrum), mouth and rectum in the same patients by means of immunocytochemistry.This technique allows detect both coccoid and spiral forms of HP. Results of HP detection in oral cavity and rectum corresponded with HP detection in stomach in 80% and 83%, respectively. Immunocytochemical observation of HP in oral, stomach and rectum mucosa let make a suggestion that HP bacterial cells enter human gut as coccoids, colonize stomach mucosa as vegetable spirals forms and leave human gut for out as coccoid forms. Thus our data strongly support hypothesis that HP infection spread and contaminate human gut through coccoid forms.

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About the authors

V Yu Kravtsov

The Nikiforov Russian Center of Emergency and Radiation Medicine EMERCOM of Russia

Yu A Grukhin

Kirov Military Medical Academy

T V Sourovtseva

Hospital № 20, St. Petersburg

Ya Ya Mazurova

Hospital № 54, St. Petersburg

M G Kobiashvili

The Nikiforov Russian Center of Emergency and Radiation Medicine EMERCOM of Russia

S S Aleksanin

The Nikiforov Russian Center of Emergency and Radiation Medicine EMERCOM of Russia

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Copyright (c) 2009 Kravtsov V.Y., Grukhin Y.A., Sourovtseva T.V., Mazurova Y.Y., Kobiashvili M.G., Aleksanin S.S.

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