The state of cancer care in Russia: lymphomas. Part 3. Non-Hodgkin's lymphoma (C82-C85). Age characteristics, morbidity, mortality, quality of accounting and treatment (clinical and population study).



Cite item

Full Text

Abstract

This study focuses on examining the morbidity, mortality, and characteristics of Non-Hodgkin lymphomas (NHL) in the Northwestern Federal District of the Russian Federation. The aim was to identify patterns in the dynamics, age-specific characteristics, and quality of patient registration of NHL (C82-85) based on data from the population-based cancer registry. The relevance of the study stems from the heterogeneity of the NHL group, which includes approximately 100 subtypes, necessitating a differentiated approach to diagnosis and treatment. The research material consisted of registry data, reference books, and publications characterizing the epidemiology of NHL. Data analysis revealed specific prevalence (taking into account sex), age distribution, localization structure, and mortality dynamics from NHL, as well as assessing the impact of the COVID-19 pandemic on the detection and registration of morbidity. It was confirmed that mortality is the most reliable indicator of the effectiveness of cancer treatment, less susceptible to distortions than morbidity and survival rates. The results obtained can serve as a basis for developing more effective strategies for the control and prevention of NHL, taking into account regional characteristics of the course and outcomes of the disease, as well as factors affecting statistics.

About the authors

Vakhtang M. Merabishvili

N. N. Petrov National Medical Research Centre of Oncology Ministry of public health of Russian Federation

Email: MVM@niioncologii.ru
ORCID iD: 0000-0002-1521-455X
SPIN-code: 5705-6327

Honored Scientist of the Russian Federation, Dr.Med.Sci., Professor, Head of the Department of Cancer Statistics

Russian Federation, Saint Petersburg

Svetlana A. Kuleva

N. N. Petrov National Medical Research Centre of Oncology Ministry of public health of Russian Federation; Saint Petersburg State Pediatric Medical University

Email: Kulevadoc@yandex.ru

DSc Med., Associate Professor, Leading Researcher at the Scientific Department of Innovative Methods of Therapeutic Oncology and Rehabilitation, Head of the Department of Oncology, Chief Freelance Pediatric Oncologist at the Committee on Public Health, Saint Petersburg

Russian Federation, Saint Petersburg

Alexey M. Belyaev

N. N. Petrov National Medical Research Centre of Oncology Ministry of public health of Russian Federation; North-Western State Medical University named after I. I. Mechnikov

Email: bam281060@yandex.ru
ORCID iD: 0000-0001-5580-4821
SPIN-code: 9445-9473

Dr. Med. Sci., Professor, Honored Doctor of the Russian Federation, Corresponding Member of RAS, Director, Head of the Department of Oncology

Russian Federation, Saint Petersburg

Larisa V. Filatova

N. N. Petrov National Medical Research Centre of Oncology Ministry of public health of Russian Federation

Email: larisa_filatova@list.ru

Dr. of Sci. (Med.), Associate Professor, Leading Researcher of the Research Department of Innovative Therapeutic Oncology and Rehabilitation Methods, Oncologist of the Department

Russian Federation, Saint Petersburg

Vladimir V. Perelygin

Saint Petersburg State Chemical and Pharmaceutical University

Author for correspondence.
Email: vladimir.pereligin@pharminnotech.com
ORCID iD: 0000-0002-0999-5644
SPIN-code: 3128-7451
Scopus Author ID: 13105602000
ResearcherId: AAV-6556-2020

Dr. Med. Sci., Professor, Head of the Industrial Ecology Department

Russian Federation, Saint Petersburg

References

  1. Cancer Incidence in Five Continents. Volume XII. Registry Summary tables. https://ci5.iarc.fr/ci5-xii/tables/summary.
  2. Malignant neoplasms in Russia in 2023 (morbidity and mortality) / Kaprin A. D., Starinsky V. V., Shakhzadova A. O. // Moscow: P. A. Hertsen MNIOI. – 2024. – 276 p (in Russ.).
  3. Merabishvili V.M. Covid and cancer in Russia. Problems in Oncology. 2022; 68(4): 381–92. doi: 10.37469/0507-3758-2022-68-4-381-392. (in Russ.).
  4. Malignant neoplasms in Russia in 2000 (morbidity and mortality) / Chissov V.I., Starinsky V.V. // Moscow: P. A. Hertsen MNIOI. 2002:264. (in Russ.).
  5. Malignant neoplasms in Russia in 2005 (morbidity and mortality) / Chissov V. I., Starinsky V.V. // Moscow: P.A. Hertsen MNIOI. 2007:252. (in Russ.).
  6. Malignant neoplasms in Russia in 2010 (morbidity and mortality) / Chissov V. I., Starinsky V. V., Petrova G.V. // Moscow: P.A. Hertsen MNIOI. – 2012. – 260p. (in Russ.).
  7. Malignant neoplasms in Russia in 2015 (morbidity and mortality) / Kaprin A. D., Sprinsky V. V., Petrova G. V. // Moscow: P. A. Hertsen MNIOI. – 2017. – 250p. (in Russ.).
  8. Malignant neoplasms in Russia in 2019 (morbidity and mortality) / Kaprin A. D., Starinsky V. V., Shakhzadova A. O. // Moscow: P. A. Hertsen MNIOI. – 2020. – 214p. (in Russ.).
  9. Malignant neoplasms in Russia in 2020 (morbidity and mortality) / Kaprin A. D., Starinsky V. V, Shakhzadova A. O. // Moscow: P. A. Hertsen MNIOI. – 2021. – 252p. (in Russ.).
  10. Malignant neoplasms in Russia in 2021 (morbidity and mortality) / Kaprin A. D., Starinsky V. V., AO. Shakhzadova // Moscow: P. A. Hertsen MNIOI. – 2022. – 252p. (in Russ.).
  11. Merabishvili V. M., Belyaev A. M., Shcherbakov A. M. Malignant neoplasms in the North-West Federal District of Russia (morbidity, mortality, reliability of accounting, survival rate of patients). Express-information. 2020:236. (in Russ.).
  12. Merabishvili V.M., Belyaev A. M. Malignant neoplasms in the North-West Federal District of Russia (morbidity, mortality, reliability of accounting, survival rate of patients). St. Petersburg. 2023:498. (in Russ.).
  13. A.M. Belyaev, V.M. Merabishvili. Methodological approaches to the analysis of the activities of the cancer service on the basis of the forms of state reporting and the database of the population cancer register of the northwestern Federal district. Part 1 // Problems in Oncology. 2019;63(5): 653–663. (in Russ.).
  14. Merabishvili, V. M. Patterns of dynamics of mortality rates of the Russian population by age from malignant neoplasms / V. M. Merabishvili // Advances in Gerontology. – 2019. – Vol. 32, No. 3. – P. 301–310. (in Russ.).
  15. Analytical indicators. accounting reliability index. Voprosy Onkologii. 2018;64(3):445–452.
  16. Merabishvili V.M. The reliability index is the most important criterion for objective assessment of oncological service performance for all localisations of cancer, regardless of the level of mortality of patients. Voprosy Onkologii. 2019;65(4):510–515. (in Russ.).
  17. Merabishvili V.M. Oncology statistic. Part II. Second edition, expanded – Saarbrüchen, Dentschland (Germany): Lap Lambert Academic Publishing, 2015 (In Russ.)
  18. Merabishvili V.M. Oncology statistic. Part II. Second edition, expanded – Saarbrüchen, Dentschland (Germany): Lap Lambert Academic Publishing, 2015 – 247 c. (In Russ.).
  19. Merabishvili, V. M. Analytical indicators. Analysis of the actual state of the dynamics of mortality of the Russian population from malignant neoplasms and changes in its structure / V. M. Merabishvili // Issues of oncology. – 2019. – Vol. 65, No. 2. – P. 205–219. (In Russ.).
  20. Statistical Methods in cancer research. Vol. 1. The analysis of case-control studies / Ed. N. E. Breslow et al. // IARC Scientifi c publ. 1980. № 32. Lyon.
  21. Merabishvili, V. M. Children's population-based cancer registry of the North-West region of Russia: methodological foundations of creation / V. M. Merabishvili, S. A. Kuleva // Oncopediatrics. – 2016. – Vol. 3, No. 2. – P. 80-87. – doi: 10.15690/0NC0.V3I2.1541. (In Russ.).
  22. Belogurova, M. B. Pediatric oncology in St. Petersburg: achievements and development prospects / M. B. Belogurova, E. G. Boychenko, S. A. Kuleva // Pediatr. – 2015. – Vol. 6, No. 4. – Pp. 5–12. – doi: 10.17816/PED645-12. (In Russ.)
  23. The Children's Hematology Service of St. Petersburg is 50 years old: stages of a long journey / E. G. Boychenko, M. B. Belogurova, E. V. Semenova [et al.] // Russian Journal of Children's Hematology and Oncology. – 2018. – Vol. 5, No. 2. – P. 72–78. (In Russ.).

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2025 Eco-Vector

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 76969 от 11.10.2019.