Toxicology of carbon nanostructures. Part I. Spherical nanoparticles (fullerenes and nanoonions)

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Abstract

The literature review is devoted to the generalization of publications on the toxicity of carbon nanostructures, which have recently been increasingly used in biological and pharmacological research, in medicinal chemistry with the prospect of being used in medicine. Analysis of the literature data shows that, despite a huge amount of work, there are no unambiguous conclusions about the toxicological characteristics of various types of carbon nanomaterials. The use of carbon nanostructures in medicine can be questioned due to the potentially adverse health effects of their use. To clarify the harmlessness, it is necessary to develop more effective tests on animals, taking into account the characteristics of each type of nanomaterial.

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About the authors

Elena V. Litasova

Institute of Experimental Medicine

Author for correspondence.
Email: llitasova@mail.ru
ORCID iD: 0000-0002-0999-8212
SPIN-code: 5568-8939

Cand. Sci. (Biol.), Leading Researcher

Russian Federation, Saint Petersburg

Viktor V. Iljin

Institute of Experimental Medicine

Email: llitasova@mail.ru
ORCID iD: 0000-0002-1012-7561
SPIN-code: 5559-8089

Cand. Sci. (Chem.), Researcher

Russian Federation, Saint Petersburg

Leonid V. Myznikov

Institute of Experimental Medicine

Email: myznikov_lv@mail.ru
ORCID iD: 0000-0002-0863-3027
Scopus Author ID: 391134

Dr. Sci. (Chem.), Researcher

Russian Federation, Saint Petersburg

Levon B. Piotrovskiy

Institute of Experimental Medicine

Email: levon-piotrovsky@yandex.ru
ORCID iD: 0000-0001-8679-1365
SPIN-code: 2927-6178

Dr. Sci. (Biol.), Professor, Head of the Laboratory

Russian Federation, Saint Petersburg

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