Токсикология наноструктур углерода. Часть I. Сферические наночастицы (фуллерены и наноонионы)

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Аннотация

Обзор литературы посвящен обобщению публикаций по токсичности углеродных наноструктур, которые в последнее время все чаще используют в биологических и фармакологических исследованиях, в медицинской химии с перспективой применения в медицине. Анализ литературных данных показывает, что, несмотря на огромное количество работ, нет однозначных выводов о токсикологических характеристиках различных типов углеродных наноматериалов. Использование наноструктур углерода в медицине может быть поставлено под сомнение из-за потенциально неблагоприятных последствий для здоровья организма при их применении. Для выяснения безвредности необходима разработка более эффективных тестов на животных, с учетом особенностей каждого типа наноматериалов.

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Елена Викторовна Литасова

Институт экспериментальной медицины

Автор, ответственный за переписку.
Email: llitasova@mail.ru
ORCID iD: 0000-0002-0999-8212
SPIN-код: 5568-8939

канд. биол. наук, ведущий научный сотрудник

Россия, Санкт-Петербург

Виктор Владимирович Ильин

Институт экспериментальной медицины

Email: llitasova@mail.ru
ORCID iD: 0000-0002-1012-7561
SPIN-код: 5559-8089

канд. хим. наук, научный сотрудник

Россия, Санкт-Петербург

Леонид Витальевич Мызников

Институт экспериментальной медицины

Email: myznikov_lv@mail.ru
ORCID iD: 0000-0002-0863-3027
Scopus Author ID: 391134

д-р хим. наук, научный сотрудник

Россия, Санкт-Петербург

Левон Борисович Пиотровский

Институт экспериментальной медицины

Email: levon-piotrovsky@yandex.ru
ORCID iD: 0000-0001-8679-1365
SPIN-код: 2927-6178

д-р биол. наук, руководитель лаборатории

Россия, Санкт-Петербург

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