Some pharmacological propertyes of Chamerion angustifolium infusions

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Abstract

BACKGROUND: Chamerion angustifolium has been popular among the people for many centuries as a substitute for tea and a mild sedative. Leaf infusions are used for neurosis, cephalgia, epilepsy and other neurological diseases.

AIM: Was to experimentally confirm the cerebroprotective properties of Chamerion leaf infusions.

METHODS: We used the methods of maximum electric shock, conditioned passive avoidance, and immobilization stress in rats and mice.

RESULTS: Infusions of leaves experimentally revealed no anticonvulsant properties. Cerebroprotective properties were manifested in the preservation of the passive avoidance conditioned reflex after maximum shock and faster recovery of exploratory behavior. Distinct stress-limiting properties were revealed during immobilization stress in mice. Fermented leaves have been shown to be less effective than non-fermented ones.

CONCLUSION: The data obtained confirm the presence of cerebroprotective properties of the infusion of Chamerion angustifolium.

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About the authors

Oleg D. Barnaulov

Bekhtereva Institute of Human Brain

Author for correspondence.
Email: barmaulov@mail.ru

Mr. Sci. (Med.), Leading Researcher

Russian Federation, Saint Petersburg

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Copyright (c) 2022 Barnaulov O.D.

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