Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests
- Authors: Galstyan D.S.1,2,3, Kolesnikova T.O.4, Kositsyn Y.M.1, Zabegalov K.N.4, Gubaidullina M.A.4, Maslov G.O.4,5, Demin K.A.1,4,3, Kalueff A.V.1,2,4,3,5,6,7,8
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Affiliations:
- Saint Petersburg State University
- A.M. Granov Russian Research Center for Radiology and Surgical Technologies
- Almazov National Medical Research Centre
- Sirius University of Science and Technology
- Ural Federal University
- Novosibirsk State University
- Research Institute of Neuroscience and Medicine
- Moscow Institute of Physics and Technology
- Issue: Vol 20, No 2 (2022)
- Pages: 123-133
- Section: Original articles
- Submitted: 09.08.2022
- Accepted: 29.08.2022
- Published: 03.10.2022
- URL: https://journals.eco-vector.com/RCF/article/view/109699
- DOI: https://doi.org/10.17816/RCF202123-133
- ID: 109699
Cite item
Abstract
Anxiety is a complex and multifaceted neurobehavioral disorder that includes various forms of chronic pathological anxiety and fears, and is also the cause for various comorbid pathologies, such as depression or cardiovascular diseases. Behavioral testing of various model organisms, including the zebrafish (Danio rerio), is widely used to study neurobiological mechanisms of anxiety. Here, we discuss the novel tank test, the open field test, light-dark box and shoaling test that are widely used in translational biological psychiatry to characterize anxiety-related behavioral phenotypes in zebrafish.
Keywords
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About the authors
David S. Galstyan
Saint Petersburg State University; A.M. Granov Russian Research Center for Radiology and Surgical Technologies; Almazov National Medical Research Centre
Email: david_sam@mail.ru
Research Associate
Russian Federation, Saint Petersburg; Saint Petersburg; Saint PetersburgTatyana O. Kolesnikova
Sirius University of Science and Technology
Email: philimontani@yandex.ru
ORCID iD: 0000-0002-5561-8583
SPIN-code: 8558-7887
Research Associate
Russian Federation, SochiYurii M. Kositsyn
Saint Petersburg State University
Email: ikosicin53@gmail.com
ORCID iD: 0000-0002-4266-808X
Research Associate
Russian Federation, Saint PetersburgKonstantin N. Zabegalov
Sirius University of Science and Technology
Email: hatokiri@mail.ru
ORCID iD: 0000-0002-9748-0324
SPIN-code: 5993-6315
Research Associate
Russian Federation, SochiMariya A. Gubaidullina
Sirius University of Science and Technology
Email: mariangub@gmail.com
Research Associate
Russian Federation, SochiGleb O. Maslov
Sirius University of Science and Technology; Ural Federal University
Email: maslovog6@gmail.com
Research Associate
Russian Federation, Sochi; YekaterinburgKonstantin A. Demin
Saint Petersburg State University; Sirius University of Science and Technology; Almazov National Medical Research Centre
Email: deminkasci@gmail.com
SPIN-code: 3830-1853
Cand. Sci. (Biol.), Senior Research Associate
Russian Federation, Saint Petersburg; Sochi; Saint PetersburgAllan V. Kalueff
Saint Petersburg State University; A.M. Granov Russian Research Center for Radiology and Surgical Technologies; Sirius University of Science and Technology; Almazov National Medical Research Centre; Ural Federal University; Novosibirsk State University; Research Institute of Neuroscience and Medicine; Moscow Institute of Physics and Technology
Author for correspondence.
Email: avkalueff@gmail.com
ORCID iD: 0000-0002-7525-1950
SPIN-code: 4134-0515
Dr. Sci. (Biol.), Professor
Russian Federation, Saint Petersburg; Saint Petersburg; Sochi; Saint Petersburg; Yekaterinburg; Novosibirsk; Novosibirsk; MoscowReferences
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