Studying social behavior in zebrafish (Danio rerioo) in the tests of social interaction, social preference, behavior in the shoaling and aggression tasks
- Authors: Galstyan D.S.1,2,3, Kolesnikova T.O.4, Kositsyn Y.M.1, Zabegalov K.N.4, Gubaidullina M.A.4, Maslov G.O.4,5, Demin K.A.1,4,3, Kalueff A.V.1,2,4,3,5,6,7,8
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Affiliations:
- Saint Petersburg State University
- A.M. Granov Russian Research Center for Radiology and Surgical Technologies
- Almazov National Medical Research Centre
- Sirius University of Science and Technology
- Ural Federal University
- Novosibirsk State University
- Research Institute of Neuroscience and Medicine
- Moscow Institute of Physics and Technology
- Issue: Vol 20, No 2 (2022)
- Pages: 135-147
- Section: Original articles
- Submitted: 09.08.2022
- Accepted: 12.08.2022
- Published: 03.10.2022
- URL: https://journals.eco-vector.com/RCF/article/view/109700
- DOI: https://doi.org/10.17816/RCF202135-147
- ID: 109700
Cite item
Abstract
Social interactions between conspecifics are an important factor in normal development of an individual in a community, and their deficits correlate with multiple psychiatric disorders. Several methods for assessing social behavior and its deficits have been described for zebrafish (Danio rerio), and include tests for social preference and social interaction. These tests are commonly used to model a wide range of social phenotypes that are potentially relevant to studying depression, pathological aggression, schizophrenia, autism, and other brain diseases. An important and widely used method for determining social behavior is the shoaling test, based on the innate, genetically fixed feature of zebrafish to form shoals/schools, the density of which depends on many factors, such as the presence of a predator, the effect of pharmacological drugs, etc. Aggression, along with shoaling, is an important manifestation of social behavior, which is also a core symptoms of multiple brain diseases, such as control disorder and conduct disorder. Here, we discuss various methods for assessing aggressive behavior in zebrafish (e.g., the mirror reflection tests), and their shoaling agonistic behaviors.
Keywords
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About the authors
David S. Galstyan
Saint Petersburg State University; A.M. Granov Russian Research Center for Radiology and Surgical Technologies; Almazov National Medical Research Centre
Email: david_sam@mail.ru
Research Associate
Russian Federation, Saint Petersburg; Saint Petersburg; Saint PetersburgTatyana O. Kolesnikova
Sirius University of Science and Technology
Email: philimontani@yandex.ru
ORCID iD: 0000-0002-5561-8583
SPIN-code: 8558-7887
Research Associate
Russian Federation, SochiYurii M. Kositsyn
Saint Petersburg State University
Email: ikosicin53@gmail.com
ORCID iD: 0000-0002-4266-808X
Research Associate
Russian Federation, Saint PetersburgKonstantin N. Zabegalov
Sirius University of Science and Technology
Email: hatokiri@mail.ru
ORCID iD: 0000-0002-9748-0324
SPIN-code: 5993-6315
Research Associate
Russian Federation, SochiMariya A. Gubaidullina
Sirius University of Science and Technology
Email: mariangub@gmail.com
Research Associate
Russian Federation, SochiGleb O. Maslov
Sirius University of Science and Technology; Ural Federal University
Email: maslovog6@gmail.com
Research Associate
Russian Federation, Sochi; YekaterinburgKonstantin A. Demin
Saint Petersburg State University; Sirius University of Science and Technology; Almazov National Medical Research Centre
Email: deminkasci@gmail.com
SPIN-code: 3830-1853
Cand. Sci. (Biol.), Senior Research Associate
Russian Federation, Saint Petersburg; Sochi; Saint PetersburgAllan V. Kalueff
Saint Petersburg State University; A.M. Granov Russian Research Center for Radiology and Surgical Technologies; Sirius University of Science and Technology; Almazov National Medical Research Centre; Ural Federal University; Novosibirsk State University; Research Institute of Neuroscience and Medicine; Moscow Institute of Physics and Technology
Author for correspondence.
Email: avkalueff@gmail.com
ORCID iD: 0000-0002-7525-1950
SPIN-code: 4134-0515
Dr. Sci. (Biol.), Professor
Russian Federation, Saint Petersburg; Saint Petersburg; Sochi; Saint Petersburg; Yekaterinburg; Novosibirsk; Novosibirsk; MoscowReferences
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