The influence of peptide bioregulators on the resistance of the organism to adverse effects

The article explores the potential of using peptide bioregulators-cytomedins to enhance the body’s resistance against adverse environmental influences. The study examines scientific literature on the general mechanisms of action of peptide bioregulators, their main clinical effects, and applications. Furthermore, it analyzes the results of research on their activity in individuals with signs of asthenia and reduced immunoreactivity under various adverse conditions, such as hypoxia, hyperthermia, and exposure to aviation and space flight factors, deep-sea diving, and the challenging environment of the Arctic zone.

The research indicates that a single intranasal administration of cortexin, epithalamin, thymogen, and prostatilen in low doses contributes to an increase in the tolerance of adverse effects. Additionally, their short-term use shows delayed positive effects, reflecting their impact on the level of nonspecific resistance of the organism. The specific effects of these drugs depend on the type of adverse effect and the organ tropism of each drug.