Reactivation of chronic brucellosis infection after COVID-19 (case report)
- Authors: Khaidarova Y.M.1,2, Lesnyak O.M.3, Kurmanova G.M.1, Kulembaeva A.B.2
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Affiliations:
- Al-Farabi Kazakh National University
- City Rheumatology Center
- orth-Western State Medical University named after I.I. Mechnikov
- Issue: Vol 26, No 3 (2022)
- Pages: 37-42
- Section: Case report
- Submitted: 28.05.2022
- Accepted: 09.09.2022
- Published: 10.11.2022
- URL: https://journals.eco-vector.com/RFD/article/view/108303
- DOI: https://doi.org/10.17816/RFD108303
- ID: 108303
Cite item
Abstract
It has been proven that the SARS-CoV-2 virus, interacting with persistent latent pathogens in the human body, including those living in the ecosystems of the intestine, mouth and lungs, causes dysregulation of the immune system and can contribute to the reactivation of these pathogens. The authors of the article suggested this pathogenic virus can play the role of a superantigen and trigger the phenomenon of polyclonal activation of lymphocytes, due to which various clones of lymphocytes may be activated, thereby giving impetus to the reactivation of a chronic persistent infection. This article describes a clinical case of a patient who had previously undergone an effectively treated form of chronic brucellosis in history, with signs of reactivation of brucellosis infection detected after infection with the SARS-CoV-2 virus, confirmed by clinical laboratory and instrumental studies.
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About the authors
Yulduz M. Khaidarova
Al-Farabi Kazakh National University; City Rheumatology Center
Author for correspondence.
Email: yulduz.khaidarova88@gmail.com
ORCID iD: 0000-0002-5475-8410
doctoral student 3 years of study
Kazakhstan, AlmatyOlga M. Lesnyak
orth-Western State Medical University named after I.I. Mechnikov
Email: olga.m.lesnyak@yandex.ru
ORCID iD: 0000-0002-0143-0614
Scopus Author ID: 56769681100
ResearcherId: J-5512-2013
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint PetersburgGaukhar M. Kurmanova
Al-Farabi Kazakh National University
Email: gkurman@mail.ru
ORCID iD: 0000-0002-5768-0209
Scopus Author ID: 6507474504
MD, Dr. Sci. (Med.), Professor
Kazakhstan, AlmatyAnarkul B. Kulembaeva
City Rheumatology Center
Email: dr_kulembayeva@mail.ru
ORCID iD: 0000-0003-3513-8467
MD, Cand. Sci. (Med.)
Kazakhstan, AlmatyReferences
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