DIFFUSE NONE TOXIC GOITER IN PATIENTS FROM NORTH REGION OF SAUDI ARABIA

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Abstract

The results of treatment of 86 patients - the indigenous inhabitants of the northern region of Saudi Arabia with newly diagnosed diffuse nontoxic goiter. Peculiarities of diagnostics, treatment and therapy of diffuse toxic goiter in this ethnic group were studied. We revealed the prevalence of goiter grade II and III. Treatment, that was most effective in reducing the volume of the thyroid, was a combination of potassium iodide (150-200 mg daily) and L-thyroxine in individually selected dose. This treatment resulted in a reduction in the size of 34% of goiter. Potassium iodide monotherapy did not result in a statistically significant reduction in the volume of the thyroid gland.

About the authors

S R Schaban

North-Western State Medical University named after I. I. Mechnikov

N V Ivanov

North-Western State Medical University named after I. I. Mechnikov

N V Vorokhobina

North-Western State Medical University named after I. I. Mechnikov

References

  1. Hill A. G., Mwangi I., Wagana L. Thyroid disease in a rural Kenyan hospital // East. Afr. Med. J. - 2004. - Vol. 81. - Р. 631-633.
  2. Azizi F, Navai L, Fattahi F. Goiter prevalence, urinary iodine excretion, thyroid function and antithyroid function and anti-thyroid antibodies after 12 years of salt iodization in Shahriar, Iran // J. Endocrinol. Invest. - 2005. - Vol. 28. - № 8. - P. 727-733.
  3. Bazrafshan H. R., Mohammadian S., Ordookhani A., Farhidmehr F., Hedayati M., Abdolahi N., Azizi F., Braverman L. E., Pearce E. N. Prevalence of goiter among schoolchildren from Gorgan, Iran, a decade after national iodine supplementation: association with age, gender, and thyroperoxidase antibodies // J. Pediatr. Endocrinol. Metab. - 2006. - Vol. 19. - № 7. - P. 889-893.
  4. Abdullah M. A., Salhi H., al. Herbish A. A. Childhood goitre in Saudi Arabia // J. Endocrinol. Invest. - 2007. - Vol. 30. - № 4. - P. 274-278.
  5. Rezvanfar M. R., Farahany H., Chehreiy A., Nemati M., Rostamy S., Karimy E. Urinary iodine excretion and antiperoxidase enzyme antibody in goitrous and healthy primary school children of Arak, Iran // Cent. Eur. J. Public Health. - 2003. - Vol. 11. - № 3. - P. 120-123.
  6. Abu-Eshy S. A., Abolfotouh M. A., Al-Naggar Y. M. Endemic goitre in schoolchildren in high and low altitude areas of Asir region, Saudi Arabia // East Afr. J. Public Health. - 2008. - Vol. 5. - № 3. - P. 163-168.
  7. Alsanosy R. M., Gaffar A. M., Khalafalla H. E., Mahfouz M. S., Zaid A. N., Bani I. A. Current iodine nutrition status and progress toward elimination of iodine deficiency disorders in Jazan, Saudi Arabia // Clin. Endocrinol. (Oxf). - 2003. - Vol. 59. - № 3. - P. 298-306.
  8. Kona S., Al Moharb A. The surgery of goitre in Riyadh Armed Forces Hospital // Saudi Medical Journal. - 1988. - Vol. 9. - P. 617-621.
  9. Al-Nuaim A. R., Al-Mazrou Y., Kamel M., Al-Attas O., Al-Daghari N., Sulimani R. Iodine deficiency in Saudi Arabia // Ann. Saudi Med. - 1997. - Vol. 17. - № 3. - P. 293-297.
  10. Dabbaghmanesh M. H., Sadegholvaad A., Ejtehadi F., Omrani G. R. Persistence of goitre in children post-salt iodization in Islamic Republic of Iran: autoimmune status // Ann. Trop. Paediatr. - 1997. - Vol. 17. - № 3. - P. 233-238.

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Copyright (c) 2014 Schaban S.R., Ivanov N.V., Vorokhobina N.V.

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