Anxiety and depression in patients with obstructive ventilation disorders: the respect study. Part 2

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Abstract


The article presents an analysis of the risk factors for anxiety and depression in people with airflow limitation based on the results of the second (diagnostic) phase of the RESPECT (RESearch on the PrEvalence and the diagnosis of COPD and its Tobacco-related aetiology). The data indicates that participants with airflow limitation that had been revealed during the epidemiological study and with borderline or abnormal anxiety and/or depression showed in diagnostic study persistent airflow limitation (FEV1/FVC = 66.48 ± 10.22, p < 0.05) and more perceived respiratory symptoms (CAT = 11.1 ± 10.01, mMRC = 1.68 ± 1.02, p < 0.001) compared to those without mental disorders. Also, they tended to have concomitant cardiovascular diseases (coronary heart disease, chronic heart failure, p < 0.001) and diabetes mellitus (p < 0.01) more frequently. Although chronic heart failure is the most prominent risk factor for anxiety/depression, it becomes non-significant when corrected for other somatic diseases and respiratory symptoms.


Elena A. Andreeva

Northern State Medical University

Author for correspondence.
Email: klmn.69@mail.ru

Russian Federation, Arkhangelsk

PhD, associate professor of the Department of Family Medicine

Marina A. Pokhaznikova

North-Western State Medical University named after I.I. Mechnikov

Email: marina.pokhaznikova@szgmu.ru

Russian Federation, Saint Petersburg

PhD, associate professor of the Department of Family Medicine

Irina E. Moiseeva

North-Western State Medical University named after I.I. Mechnikov

Email: irina.moiseeva@szgmu.ru

Russian Federation, Saint Petersburg

PhD, associate professor of the Department of Family Medicine

Olga Yu. Kuznetsova

North-Western State Medical University named after I.I. Mechnikov

Email: olga.kuznetsova@szgmu.ru

Russian Federation, Saint Petersburg

DSc, professor, Head of the Department of Family Medicine

Jean-Marie Degryse

Institute of Health and Society of Catholic University of Louvain (UCL); Department of Public Health and Primary Health Care

Email: jan.degryse@kuleuven.be

Belgium, Brussels; Leuven

MD, PhD, professor

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Copyright (c) 2017 Andreeva E.A., Pokhaznikova M.A., Moiseeva I.E., Kuznetsova O.Y., Degryse J.

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