Saccharomyces cerevisiae killer toxins: synthesis, mechanisms of action and practical use

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Abstract

Yeast Saccharomyces cerevisiae is a unique model for studying the molecular mechanisms of exotoxin-mediated antagonistic relationships between coexisting microorganisms. The synthesis of yeast toxins can be considered as an example of allelopathy and environmental competition. The elucidation of the role of allelopathy in the formation of microbial communities is of great interest for modern ecology. Yeast toxins are widely used in medicine, the food industry and biotechnology. The review examines the nature of exotoxins, the mechanisms of inheritance and interaction of the virus and yeast cells, as well as the prospects for their practical application.

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About the authors

Elena V. Sambuk

Saint-Petersburg State University

Author for correspondence.
Email: esambuk@mail.ru
ORCID iD: 0000-0003-0837-0498
SPIN-code: 8281-8020
Scopus Author ID: 6603061322
ResearcherId: H-6895-2013

Associate Professor, Professor of the Department of Genetics and Biotechnology

Russian Federation, Saint-Petersburg, Universitetskaya embankment, 7/9,199034

Dmitry M. Muzaev

Saint-Petersburg State University

Email: dmmuzaev@yandex.ru

engineer

Russian Federation, Saint-Petersburg, Universitetskaya embankment, 7/9,199034

Andrey M. Rumyantsev

Saint-Petersburg State University

Email: rumyantsev-am@mai.ru
ORCID iD: 0000-0002-1744-3890
SPIN-code: 9335-1184
Scopus Author ID: 55370658800

junior research assistant
 
Russian Federation, Saint-Petersburg, Universitetskaya embankment, 7/9,199034

Marina V. Padkina

Saint-Petersburg State University

Email: mpadkina@mail.ru
ORCID iD: 0000-0002-4051-4837
SPIN-code: 7709-0449
Scopus Author ID: 6602596755

Associate Professor, Professor of the Department of Genetics and Biotechnology

Russian Federation, Saint-Petersburg, Universitetskaya embankment, 7/9,199034

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