Saccharomyces cerevisiae killer toxins: synthesis, mechanisms of action and practical use

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Yeast Saccharomyces cerevisiae is a unique model for studying the molecular mechanisms of exotoxin-mediated antagonistic relationships between coexisting microorganisms. The synthesis of yeast toxins can be considered as an example of allelopathy and environmental competition. The elucidation of the role of allelopathy in the formation of microbial communities is of great interest for modern ecology. Yeast toxins are widely used in medicine, the food industry and biotechnology. The review examines the nature of exotoxins, the mechanisms of inheritance and interaction of the virus and yeast cells, as well as the prospects for their practical application.

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About the authors

Elena V. Sambuk

Saint-Petersburg State University

Author for correspondence.
ORCID iD: 0000-0003-0837-0498
SPIN-code: 8281-8020
Scopus Author ID: 6603061322
ResearcherId: H-6895-2013

Russian Federation, Saint-Petersburg, Universitetskaya embankment, 7/9,199034

Associate Professor, Professor of the Department of Genetics and Biotechnology

Dmitry M. Muzaev

Saint-Petersburg State University


Russian Federation, Saint-Petersburg, Universitetskaya embankment, 7/9,199034


Andrey M. Rumyantsev

Saint-Petersburg State University

ORCID iD: 0000-0002-1744-3890
SPIN-code: 9335-1184
Scopus Author ID: 55370658800

Russian Federation, Saint-Petersburg, Universitetskaya embankment, 7/9,199034

junior research assistant

Marina V. Padkina

Saint-Petersburg State University

ORCID iD: 0000-0002-4051-4837
SPIN-code: 7709-0449
Scopus Author ID: 6602596755

Russian Federation, Saint-Petersburg, Universitetskaya embankment, 7/9,199034

Associate Professor, Professor of the Department of Genetics and Biotechnology


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