Effect of LIM kin ase 1 is oform ratio on Drosophil a mel anogaster courtship behavior: a complex approach

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Abstract


LIMK1 - is the key enzyme of actin remodeling which controls dendritic spine morphology necessary for synaptic plasticity during learning and memory formation. Conditioned courtship suppression paradigm and a set-up for communicative sound production during courtship were used to asses learning acquisition and memory formation in four Drosophila strains polymorphic for the limk1 gene harbored by the agnostic locus: the wild type strains Canton-S, Berlin, Oregon-R and the mutant аgnts3. Behavioral performances were compared to the brain content and ratio of two LIMK1 isoforms in these Drosophila strains.

Keywords



About the authors

Alena N Kaminskaya

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, Saint-Petersburg, RF

Email: kaminskayaan@mail.ru, Saint-Petersburg, 199034 Makarova emb., 6, Russia

Ekaterina A Nikitina

I.P. Pavlov Institute of Physiology, RAS, Saint-Petersburg, RF

Email: 21074@mail.ru Saint-Petersburg, 199034 Makarova emb., 6, Russia

Tatyana L Payalina

I.P. Pavlov Institute of Physiology, RAS, Saint-Petersburg, RF

Email: payalina@mail.ru Saint-Petersburg, 199034 Makarova emb., 6, Russia

Dmitry A Molotkov

I.P. Pavlov Institute of Physiology, RAS, Saint-Petersburg, RF

Email: momitek@mail.ru Saint-Petersburg, 199034 Makarova emb., 6, Russia

Gennady A Zakharov

I.P. Pavlov Institute of Physiology, RAS, Saint-Petersburg, RF

Email: Gennadiy.Zakharov@gmail.com Saint-Petersburg, 199034 Makarova emb., 6, Russia

Andrey V Popov

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, Saint-Petersburg, RF

Email: office@iephb.ru 194223, Saint-Petersburg, pr. Torez 44, Russia

Elena V Savvateeva-Popova

I.P. Pavlov Institute of Physiology, RAS, Saint-Petersburg, RF

Email: esavvateeva@mail.ru Saint-Petersburg, 199034 Makarova emb., 6, Russia

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Copyright (c) 2011 Kaminskaya A.N., Nikitina E.A., Payalina T.L., Molotkov D.A., Zakharov G.A., Popov A.V., Savvateeva-Popova E.V.

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