Treatment of refractory glaucoma with cystoid macular edema

Cover Page


The article reviews clinical picture as well as treatment results of refractory glaucoma with cystoid macular edema.

Vadim P Nikolaenko

Author for correspondence.
Saint Petersburg City Hospital No 2
Russian Federation, Saint Petersburg, Russia

Chief of Ophthalmology department

Irina V Terehova
Saint Petersburg City Hospital No 2
Russian Federation, Saint Petersburg, Russia

MD, Chief of Ophthalmology diagnostic department

Tatiana Y Panova
Saint Petersburg City Hospital No 2
Russian Federation, Saint Petersburg, Russia

ophthalmic surgeon of Ophthalmology department

Anastasia V Antonova
Saint Petersburg City Hospital No 2
Russian Federation, Saint Petersburg, Russia

ophthalmic surgeon of Ophthalmology department

  • Amoozgar B, Lin SC, Han Y, Kuo J. A role for antimetabolites in glaucoma tube surgery: current evidence and future directions. Curr Opin Ophthalmol. 2016 Mar;27(2):164-9. doi: 10.1097/ICU.0000000000000244.
  • Aref AA, Gedde SJ, Budenz DL. Glaucoma drainage implant surgery. Dev Ophthalmol. 2012;50:37-47. doi: 10.1159/000334777.
  • Bailey AK, Sarkisian SR. Complications of tube implants and their management. Curr Opin Ophthalmol. 2014 Mar;25(2):148-153. doi: 10.1097/ICU.0000000000000034.
  • Ganekal S, Dorairaj S. Effect of intraoperative 5-fluorouracil and low molecular weight heparin on the outcome of high-risk proliferative vitreoretinopathy. Saudi J Ophthalmol. 2014 Oct;28(4):257-261. doi: 10.1016/j.sjopt.2014.03.005.
  • Gedde SJ, Singh K, Schiffman JC, Feuer WJ. Tube Versus Trabeculectomy Study Group. The Tube Versus Trabeculectomy Study: interpretation of results and application to clinical practice. Curr Opin Ophthalmol. 2012 Mar;23(2):118-126. doi: 10.1097/ICU.0b013e32834ff2d1.
  • Giovingo M. Complications of glaucoma drainage device surgery: a review. Semin Ophthalmol. 2014 Sep-Nov;29(5-6):397-402. doi: 10.3109/08820538.2014.959199.
  • Guerrero AH, Latina MA. Complications of glaucoma drainage implant surgery. Int Ophthalmol Clin. 2000 Winter;40(1):149-63. doi: 10.1097/00004397-200040010-00015.
  • Jung KI, Park H, Jung Y, Park CK. Serial changes in the bleb wall after glaucoma drainage implant surgery: characteristics during the hypertensive phase. Acta Ophthalmol. 2015 Jun;93(4): e248-253. doi: 10.1111/aos.12571.
  • Jung KI, Park CK. Risk factors for the hypertensive phase after implantation of a glaucoma drainage device. Acta Ophthalmol. 2016 Aug;94(5): e260-7. doi: 10.1111/aos.12916.
  • Konstas AG, Boboridis KG, Kapis P, et al. 24-hour efficacy and ocular surface health with preservative-free tafluprost alone and in conjunction with preservative-free dorzolamide/timolol fixed combination in open-angle glaucoma patients insufficiently controlled with preserved latanoprost monotherapy. Adv Ther. 2017 Jan;34(1):221-235. doi: 10.1007/s12325-016-0448-9.
  • Law SK, Kornmann HL, Giaconi JA, et al. Early aqueous suppressant therapy on hypertensive phase following glaucoma drainage device procedure: a randomized prospective trial. J Glaucoma. 2016 Mar;25(3):248-57. doi: 10.1097/IJG.0000000000000131.
  • Lee NY, Hwang HB, Oh SH, Park CK. Efficacy of additional glaucoma drainage device insertion in refractory glaucoma: Case series with a systematic literature review and meta-analysis. Semin Ophthalmol. 2015;30(5-6):345-351. doi: 10.3109/08820538.2013.874487.
  • Leon JA, Britt JM, Hopp RH, et al. Effects of fluorouracil and fluorouridine on protein synthesis in rabbit retina. Invest Ophthalmol Vis Sci. 1990 Sep;31(9):1709-1716.
  • Nouri-Mahdavi K, Caprioli J. Evaluation of the hypertensive phase after insertion of the Ahmed Glaucoma Valve. Am J Ophthalmol. 2003 Dec;136(6):1001-1008. doi: 10.1016/S0002-9394(03)00630-5.
  • Pakravan M, Rad SS, Yazdani S, et al. Effect of early treatment with aqueous suppressants on Ahmed glaucoma valve implantation outcomes. Ophthalmology. 2014 Sep;121(9):1693-1698. doi: 10.1016/j.ophtha.2014.03.014.
  • Pandey SK, Cochener B, Apple DJ, et al. Intracapsular ring sustained 5-fluorouraci delivery system for the prevention of posterior capsule opacification in rabbits: a histological study. J Cataract Refract Surg. 2002 Jan;28(1):139-148. doi: 10.1016/S0886-3350(01)01069-0.
  • Penha FM, Rodrigues EB, Maia M, et al. Retinal and ocular toxicity in ocular application of drugs and chemicals – part II: retinal to xicity of current and new drugs. Ophthalmic Res. 2010;44(4):205-224. doi: 10.1159/000316695.
  • Sarkisian SR. Tube shunt complications and their prevention. Curr Opin Ophthalmol. 2009 Mar;20(2):126-130. doi: 10.1097/ICU.0b013e328323d519.
  • Seo du R, Ha SJ. Comparison of ocular pulse amplitude lowering effects of preservative-free tafluprost and preservative-free dorzolamide-timolol fixed combination eyedrops. Biomed Res Int. 2015;2015:435874.
  • Smith M, Geffen N, Alasbali T, et al. Digital ocular massage for hypertensive phase after Ahmed valve surgery. J Glaucoma. 2010 Jan;19(1):11-14. doi: 10.1097/IJG.0b013e31819c485b.
  • Shumer RA, Camras CB, Mandahl AK. Putative side effects of prostaglandin analogs. Surv Ophthalmol. 2002. Aug. 47, Suppl. 1. S.
  • Turalba AV, Pasquale LR. Hypertensive phase and early complications after Ahmed glaucoma valve implantation with intraoperative subtenon triamcinolone acetonide. Clin Ophthalmol. 2014 Jul;11(8):1311-6. doi: 10.2147/OPTH.S64257.
  • Yuen D, Buys Y, Jin YP, et al. Corticosteroids versus NSAIDs on intraocular pressure and the hypertensive phase after Ahmed glaucoma valve surgery. J Glaucoma. 2011 Sep;20(7):439-444.doi: 10.1097/IJG.0b013e3181efbec0.
  • Valenzuela F, Browne A, Srur M, et al. Combined phacoemulsification and Ahmed glaucoma drainage implant surgery for patients with refractory glaucoma and cataract. J Glaucoma. 2016 Feb;25(2):162-166. doi: 10.1097/IJG.0000000000000141.
  • Won HJ, Sung KR. Hypertensive phase following silicone plate Ahmed glaucoma valve implantation. J Glaucoma. 2016 Apr;25(4): e313-317. doi: 10.1097/IJG.0000000000000249.


Abstract - 204

PDF (Russian) - 330

Copyright (c) 2017 ECO-vector LLC

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.