Effect of extractum eleutherococci fluidum on the prolactin basal level in the blood of the women during lactogenesis

Abstract

Objective: To explore the effect of extractum eleutherococci fluidum (EEF) on secretion prolactin (PRL), 8 breastfeeding women (experimental group) were treated with oral EEF (5 ml, four times daily) during 8 days after delivery.

Full Text

Methods: Determination of the basal level of serum PRL was performed on the 1^st, 4^thand 8^th day after delivery. The experimental and control groups consisted of 8 breastfeeding women of 18-38 years age. Blood samples (5 ml) were attained from catheterized forearm vein. Serum PRL was measured using the immunometric method. Student's t-test was used for statistical analysis.

Results: In the experimental group of the women PRL concentration on the 1^st day was 3919-+273 mU/l, and in the control it equaled 3869-+273 mU/l. PRL concentration on the 4^th day was increased and reached 4396-+315 mU/l in experimental and 4123-+157 mU/l in control groups. Yet the difference between PRL concentration for the 1^st and the 4^th day in both groups is not significant (P>0.05) On day 8 post-partum PRL level for both groups was decreased: 3913-+449 mU/l in experimental and 3223-+346 mU/l in the control group. But the difference between the 8^th and 1^st, 4^th day for the experimental group was not significant (P>0.05) and one for control group was significant (P<0.05)

Conclusions: EEF retards the fall in the basal level of PRL in lactating women. Therefore the oral treatment may be a good profilactic measure for bettering initiation of lactation and further ensure the sufficient level of milk secretion for breastfeedig the infant.