Features of early adaptation at newborn high infectious risk

Abstract

With the purpose optimization of tactics conducting was surveyed 156 newborns from the mothers with chronic infectious diseases (ChlD). Was established, that ChlD of the mother renders serious adverse influence on a condition of a fetus and current of early adaptation at newborn, resulting to development hypoxic, infectious and toxic defeats of brain (49,6%), intrauterine hypotrophy (29,4%), intrauterine and postnatal infection (30,4%).

Full Text

With the purpose optimization of tactics conducting was surveyed 156 newborns from the mothers with chronic infectious diseases (ChlD). Was established, that ChlD of the mother renders serious adverse influence on a condition of a fetus and current of early adaptation at newborn, resulting to development hypoxic, infectious and toxic defeats of brain (49,6%), intrauterine hypotrophy (29,4%), intrauterine and postnatal infection (30,4%). Was established 4 variants of current early neonatal of the period depending on a condition of the child at birth and dynamics of a condition at the first hours о "clock. For newborn high infectious risk (even clinical healthy) are characteristic the infringements hemodynamics (later closing of fetal communications, decrease contractile activity of myocardium, high common peripheral vascular resistance, arterial hypotension), endocrine of adaptation (low level adrenocorticotropin and cortisone), metabolism (decompensated metabolic and respiratory-metabolic acidosis, increase activity of blood enzyme), the change of the factors of specific and not specific protection (hypoimmunoglobulinaemia G is less 9,8 g/l, the decrease of a level scale gamma-interferon is less 8 ME, the increase of parameters activity peroxide oxidation of lipids - MDA is more 6 ng/ml).