Hormonal background in women with secondary ovarian sclerocystois in hyperplastic processes of endometria

Abstract

We have observed the hormonal background in 160 patients with endometric hyperplasia on the background of the secondary ovarian sclerocystosis. The investigation has been carried out in the proliferatic stage of the menstrual cycle. It should be mentioned, that if the disease didn’t exceed 3 years, the data showed the affection of hypothalamic-hypophyseal system, which was accompanied with the increase of gonadotropic secretion.

Full Text

We have observed the hormonal background in 160 patients with endometric hyperplasia on the background of the secondary ovarian sclerocystosis. The investigation has been carried out in the proliferatic stage of the menstrual cycle. It should be mentioned, that if the disease didn’t exceed 3 years, the data showed the affection of hypothalamic-hypophyseal system, which was accompanied with the increase of gonadotropic secretion, strengthening of gonadotropic secretion was due to the increase of consideration FOG (27,12 mE/ml) control ( 16,1) and relative insufficiency LG (11,2 mm/E/ml) control (7,9); the decrease of LG/FOG state also showed the same. Increased stimulation of ovarian function by mean of FOG was accompanied with a certain increase of estradiol concentration (91,9 ne/ml) control (59,5) in the blood plasma. Clinically these phenomena were estimated by incomplete ovulation with the deficiency of yellow bodies in the form of incomplete secretion. Long-term (more than 3 years) stimulation of ovaries by mean of FOG resulted in progressive pathological process in endometria as a result of development of anatomical changes in ovaries with the formation of expressed secondary sclerocystosis. In this case hormonal background of the patient FOG (10,1 mm/Eml), LG (11,2), estradiol 68,5 was also changed. Clinically hormonal dislocations were characterized by the development of anovulation of DOB, with recurrent hyperplastic processes in endometria.