Early ovarian cancer’s potentials and limitations of organ - preserving treatment

Abstract

Objective: The number of the cases of early ovarian cancer is determined with improvement of diagnostic methods, so working up of organ-preserving treatment is actual. The is no common opinion for managing of early ovarian cancer as yet.

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Method: Our study was carried out in 176 women bearing borderline and malignant tumors of ovaries stage 1 and treated since 1980 till 1995 in the department of gynecological oncology. 46 of them were treated by organ — preserving methods and other 130 underwent radical surgery.

Results: The study revealed no difference in the results of treatment stage 1 a, b patients due to the method and showed the dependence of out come from histological type of tumor. The worst results were reached in stage 1c tumors with low degree of morphological differentiation. Adjuvant chemotherapy did not influence survival.

Conclusion: The question about potential use of preserving surgery: bilateral salpingoophory with preserving the uterus is discussed in connection with high risk tumor recurrences in reserved ovary (in 2 of 28 patients of fertile age). Modern achievements in reproduction technologies allow to discuss different variants of sparing treatment, that can be fulfilled only in large centers with adequate staging and monitoring.