State of central hemodynamic as result of respiratory dystress syndrom (RDS) in premature infants

Abstract

Objective. To reveal a specialty of central hemodynamic in development respiratory disorders in premature infants.

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Methods. 30 newborns 29-36 week of gestation were examined. No clinical manifestation of respiratory insufficiency in 12 infants. RDS was occurred in 18 infants. Apgar score criteria was 5-6. Echocardiography were performed at the real time scanner “Alloka — 680”. Blood pressure were measured by oscillometric method used by blood pressure monitor “EME” (England). Po₂, Pco₂ partial pressure were measured by transcutan control system “Radiometr” (Denmark).

Results. Three types of hemocirculation were revealed: hyperkinetic, hypokinetic, normokinetic. Hyperkinetic type was dominated in 34-week gestation infants. Most evident changes were exposed in infants there had hypokinetic type. Persistent pulmonary hypertension was observed in first hours of life. Rapid increasing cardiovascular insufficiency are followed by these changes.

Conclusions. Results of investigation evident about early involvement cardiovascular system in pathological process and allowed to understand RDS pathogenesis in premature infants.