Characterization of uterine papillary serous carcinoma: Clinical and morphological aspects

Abstract

Objective: Endometrial cancer are shown is nonequallical by histotypical structure, differented adenocarcinoma were observed in most of ones. The aim of our data was to investigate one of the rarest form of endometrial cancer such as uterine papillary serous carcinoma (UPSC).

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Methods: 163 women with endometrial cancer were investigated and treated by surgery, X-ray and polychemotherapy in City Cancer Hospital at 1997.

Results: UPSC was detected in 19 (11,7%) cases, from whom 6 patients were obese, 3 — with diabetes mellitus and 4 — with arterial hypertension, 4 were myoma of uteri and 5 patients were sterility. Metastases in iliac lymphonodes were found in 2 cases, in ovary - in 1 case and in gastrocolic omentum — in 1 case, respectively. Morphological structure of UPSC is similar of ovarian serous cystadenocarcinoma. Majority of features were revealed deep invasion more than 1 cm and there are psammous bodies in 5 (26,3%) cases.

Conclusion: UPSC is a highly aggressive type of endometrial cancer. Concerning results of our investigations we may noted that plan of complex treatment of UPSC must include not only surgical and X-ray therapy but chemotherapy as well.