Norplant preparation application results

Abstract

Objective: To investigate the impact of the subdermal contraceptive Norplant on the condition of hormonally dependent organs (cervix of the uterus, mammary glands, endometry) in women of various ages and acceptance rates.

Full Text

Methods: General clinical, ultrasonic study of genitals and mammary glands, noncontrastive mammography in two projections, hysteroscopy, morphological study of aspirate and bioptate of the endometry and the cervix of the uterus, expanded colposcopy, cytological study of vaginal smear, functional diagnostic tests. 100 women patients have been examined. Group 1 was comprised of 50 women aged 20 through 34; Group 2 included 50 women in the age bracket 35 through 45. None of the women had any contra-indication against the Norplant application. Repeated examinations were conducted after 1, 3, 6, 9 and 12 months after the implantation of the preparation, and further on each half year.

Results: The contraceptive effect reached 100%. In Group 1, a disturbance of the menstrual function was observed more often in the form of acyclic menstrual-like secretions; in Group 2, amenorrhea was observed. In Group 1, this method of contraception was rejected by eight patients due to the disturbance of the menstrual cycle, gaining weight, and acne; in Group 2, by three patients. A regression of hyperplastic processes of the mammary glands was observed in eight women out of 13 with this pathology in Group 1, and in 13 out of 21 - in Group 2.

Conclusion: Observed was a high contraceptive effectiveness of the preparation, its positive impact on the hyperplastic processes of the mammary glands, and a low rejection rate. At the same time, the most often side effect is the disturbance of the menstrual function, in particular, in women under the age of 35 years.