Occurence of nontoxic goiter in patients with mastopathy

Abstract

Objective: To reveal the occurrence of nontoxic goiter in patients with mastopathy.

Full Text

Method: 101 women with mastopathy (94 of them had diffuse and 7 - nodular goiter) at the age of 17-55 were examined. The diagnosis of mastopathy was based on palpation, ultrasound (on the 7^th-7^th day of menstrual cycle) and roentgenologic (on the 7^th-10^th day) findings. The thyroid size and structure were evaluated by palpation and echography. Clinical data, thyroid and thyrotrophic hormones blood levels indicated that all women were euthyroid.

Results: Thyroid hyperplasia was found in 75 women (74%); diffuse enlargement of the thyroid — in 30 (40%); diffuse nodular goiter — in 35 (48%); nodular goiter — in 9 (12%). Among 66 patients with diffuse nontoxic goiter and diffuse nodular goiter, I degree thyroid enlargement was seen in 28 (42%), II degree — in 23 (35%), III degree — in 15 (23%). These data considerably exceed the occurrence of nontoxic goiter in the Leningrad population (Shliakhtina L.G., 1967).

Conclusion: Frequent combination of fibrocystic mastopathy with nontoxic goiter suggests possible role of iodine deficiency in pathogenesis of fibrocystic mastopathy.