Diagnostic value of detecting products tissue distruction in puerperae with endometritis after cesarean section

Abstract

67 puerparae after cesarean section (CS) were followed up. 20 of these were controls in whom the puerperium ran an uncomplicated course and 47 with endometritis after CS were the main group. In addition to the general clinical studies, the pool of acid-extracting components of nucleic acids and medium-mass molecules (МММ) in blood serum and lochia were at least three times measured over the course of puerperium in all examinees.

Full Text

67 puerparae after cesarean section (CS) were followed up. 20 of these were controls in whom the puerperium ran an uncomplicated course and 47 with endometritis after CS were the main group. In addition to the general clinical studies, the pool of acid-extracting components of nucleic acids and medium-mass molecules (МММ) in blood serum and lochia were at least three times measured over the course of puerperium in all examinees. The above substances were denoted products of tissue destruction (PTD). In the controls the levels of PDT in serum reliably increased by days 5-6 and in the lochia were maximal during the first 4 days postpartum; by days 8-9 PDT reliably decreased both in the lochia and serum. In the main group the content of PDT was reliably higher both in the serum and lochia in comparison with the controls. Diagnostic values of the pool of acid-extracting components of nucleic acids and МММ were determined for each day of the postpartum period and the sensitivity of each test assessed. The proposed methods for measuring PDT in the serum and lochia permit the diagnosis of endometritis after CS to be made as early as on days 3-4 postpartum. Measurements of PDT in the serum are preferable on days 3-4 postpartum, whereas on days 7-10 investigation of the lochia is more informative.