New method of diagnosis and treatment of respiratory disorders in neonates
- Authors: Kosov M.N.1
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Affiliations:
- D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
- Issue: Vol 48, No 5S (1999)
- Pages: 87-87
- Section: Articles
- Submitted: 17.02.2022
- Accepted: 17.02.2022
- Published: 15.12.1999
- URL: https://journals.eco-vector.com/jowd/article/view/101021
- DOI: https://doi.org/10.17816/JOWD101021
- ID: 101021
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Abstract
Objective: To investigate the possibility of using capnography for pre-clinical diagnostics of pathophysiological mechanisms of respiratory disorders.
Full Text
Objective: To investigate the possibility of using capnography for pre-clinical diagnostics of pathophysiological mechanisms of respiratory disorders.
Methods: We assessed peculiarities of capnogram (C) in 35 neonates with gestational age 32 — 34 weeks (n=15), 35 — 37 weeks (n=16) and 38-40 weeks (n=4) with respiratory disorders during the first 2-3 hours of life. The data were analyzed taking into account functional state of central nervous system (CNS) and cardio-vascular system.
Results: We distinguished 3 types of C. depending on the presence of alveolar plateau: alveolar plateau is present (1), alveolar plateau is absent (2) and alveolar plateau is interrupted by sighs (3). There percentage was changed, particularly increasing of 2 type reflects functional disorders of CNS. End-tidal concentration of CO2 reflects disorders of lung function due to alveolar ventilation (CO2> 5,0 vol%), lung hemodynamics (C02< 4,0 vol%) or both (CO2< 3,2 vol%). Individual choosing of oxygen therapy using these data helps to decrease severity of respiratory disorders.
Conclusion: Monitoring of C should be used for assessment of severity and main pathophysiological mechanism of respiratory disorders for optimization of respiratory therapy in neonates.
About the authors
M. N. Kosov
D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, St. Petersburg