New method of diagnosis and treatment of respiratory disorders in neonates
- 作者: Kosov M.N.1
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隶属关系:
- D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
- 期: 卷 48, 编号 5S (1999)
- 页面: 87-87
- 栏目: Articles
- ##submission.dateSubmitted##: 17.02.2022
- ##submission.dateAccepted##: 17.02.2022
- ##submission.datePublished##: 15.12.1999
- URL: https://journals.eco-vector.com/jowd/article/view/101021
- DOI: https://doi.org/10.17816/JOWD101021
- ID: 101021
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Objective: To investigate the possibility of using capnography for pre-clinical diagnostics of pathophysiological mechanisms of respiratory disorders.
全文:
Objective: To investigate the possibility of using capnography for pre-clinical diagnostics of pathophysiological mechanisms of respiratory disorders.
Methods: We assessed peculiarities of capnogram (C) in 35 neonates with gestational age 32 — 34 weeks (n=15), 35 — 37 weeks (n=16) and 38-40 weeks (n=4) with respiratory disorders during the first 2-3 hours of life. The data were analyzed taking into account functional state of central nervous system (CNS) and cardio-vascular system.
Results: We distinguished 3 types of C. depending on the presence of alveolar plateau: alveolar plateau is present (1), alveolar plateau is absent (2) and alveolar plateau is interrupted by sighs (3). There percentage was changed, particularly increasing of 2 type reflects functional disorders of CNS. End-tidal concentration of CO2 reflects disorders of lung function due to alveolar ventilation (CO2> 5,0 vol%), lung hemodynamics (C02< 4,0 vol%) or both (CO2< 3,2 vol%). Individual choosing of oxygen therapy using these data helps to decrease severity of respiratory disorders.
Conclusion: Monitoring of C should be used for assessment of severity and main pathophysiological mechanism of respiratory disorders for optimization of respiratory therapy in neonates.
作者简介
M. Kosov
D.O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences
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Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg
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