Malignant tumors of female genital tract in children and adolescents

Abstract

Objective: Tumors of female genital tract in children and adolescents are shown are rare and have specific morphological peculiarities connected with stages of embryonic evolution of tissues.

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Methods: Since 1967 there were 118 cases of female genital tumors at the patients from 0 till 16 years hospitalized in the N. N. Petrov Institute of Oncology.

Results: Among 118 cases - 85,6% were ovarian tumors (64,35% - malignant and 35,65% - benign ovarian tumors), 12,7% were tumors of vulva and vagina (66,7%) were malignant, 1,7% - cervical carcinoma. Morphological characteristics of tumors were diverse, but all of vulva and vagina malignancies were embryonic such as rhabdomyosarcoma and have 90% mortality rates. Most ovarian tumors were germ tumors (55,5%); other histological types were founded rarest. 44,6% of malignant ovarian tumors and both cervical carcinomas have exits pessima.

Conclusions: More female genital tract tumors in children and adolescents are nonmalignant, but not very rare cases of malignant tumors cause the majority of pediatric mortality. Alternative approaches should be used for these patients in the future.