Features of thermoregulatory reaction of the rabbit fetus, developing in reduced utero-placental blood flow conditions

Abstract

Rabbit fetus with intact (control) and reduced utero-placental blood flow (exsperimental) (mass 39,1±2 gr. and 33,5±1,9 gr. correspondingly P<0,05) was investigated in the end of its intrauterine development (28- 29 days of pregnant) during physiologycal conditions and with myorelaxant (arduan) injection by its.

Full Text

The results of our researches showed, that 15-minutes period of moveless leaded to increases of the rectal temperatures from 37,58±0,33 to 37,6±0,21 °C in control and from 37,35±0,15 to 37,48±0,12 °C in experimental fetuses (P<0,05) because of the maternal-placental and feto-placental haemodynamic deficiency. The control fetus with injection myorelaxant reacted by tahycardia and increase metabolism of brown adipose tissue, that is characteristic reaction of healthy fetus to adverse changes of environment. Experimental fetus in same conditions show bradicardia and decrease of brown fat metabolism, resulting, probably, by unsufficient development and functional immaturity of this tissue. A fetal movement activity is important in the maintanance of fetuses hemodynamic and temperature hemostasis because of its participation in the regulation of the intensity of bloodflow in the hemodynamic system “mother-placenta-fetus”.