Expirience of using angioprotector Gincor Fort in the obstetric practice

Abstract

Objective: To study the efficacy of Ginkor Fort (“Beaufour”, France) in treatment of chronic venous insufficiency in 40 pregnants with viral and/or bacterial infection in the 3rd trimester of gestation.

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Methods: Ginkor Fort was given in a dose of 1 cap a day for 30 days without concomitant therapy. The control group consisted of 20 3rd trimester pregnancy women who didn’t get any medication. Besides routine clinical examination blood rheology, metabolic parameters, ultrasonic dopplerometry in popliteal veins of lower extremities were dynamically investigated in all patients. The last indices were compared with ultrasonic data of uterine and fetoplacental haemodinamic. Also, attention was paid to peculiarities of pregnancy, delivery, fetus and newborn’s states.

Results: After treatment the high clinical effect of Ginkor Fort was established in the majority (92,5%) of the patients. It was proved by the improving of pregnant general state with decrease of complaints frequency (4-5 times less) and leg's oedema disappearing. The following positive variations have been estimated during the treatment: oxygenate blood function, blood rheology, ultrasonic parameters of blood flow in popliteal veins and mother-placenta-fetus veesel system.

Conclusion: Changes mentioned above allow to consider Ginkor Fort as an effective drug in the medication of varicose vein disease in pregnancy complicated by viral and/or bacterial infection.