Prenatal factors influential in becoming reproductive system of young girl with big birth weight

Abstract

Objective: To reveal the unfavorable factors in prenatal period influential in becoming menstrual function of the girl with big birth weight.

Full Text

Methods: The program of an inspection included learning becoming menstrual function with allowance for developments gonadotrophic and ovarian hormons, analysis prenatal factors at 349 girls 10-16 years with big birth weight (4000,0 g and more) - main group, and at 315 girls with an average birth weight - control group.

Results: The average age of menarche at the girls with big birth weight has made 12 years 2 months + 0,12 years (in control group - of 12 years 10 months + 0,11 years). At the girls of main group, the earher beginning of operation of the hypophisis - ovarii system. At the girls 8-9 years a level FSG was marked has made 4,39 ± 0,26 mME/l, LG-2,72 ±0,2 mME/l, oestiadiol-0,18 ±0,01 nmol/l, progesteron - 2,02 + 0,141 nmol\l, in control group - the level FSG has made 3,03 ± 0,26 mME/l, - LG - 2,03 ± 0,21 mME/ I, oestradiol -0,11 + 0,01 nmolM, progesteron - 1,47 ± 0,14 nmol/l. The becoming ovulatoris cycles was delayed, that appeared in the greater frequency of disorders of menstrual function (48,4% against 15,6%). Mainly at the girl, who was delivery from the fat mothers, with complications in delivery (weakness of patrimonial activity, delayed delivery, hypoxia of a fetus). Most frequently met anovulatoris cycles, juvenile bleeding, irregular menstruation, algomenorrhea, gyperpolymenorrhea. To completion of puberty at the girl of main group the lower level progesteron was marked (15,81 + 1,12 nmol/l, in control group - 23,10 + 0,71 nmol/l).

Conclusion: Thus, fat mothers, delayed delivery, big birth weight, hypoxia of a fetus concern to prenatal factors most frequently detected at the girl with big birth weight with abnormal menstrual cycle in puberty.