The level of CA 125 antigen in serum from women with uterine myoma

Abstract

Objective: The literature data on the prognostic role of blood CA 125 concentration in the patients with uterine myoma are rather different.

Full Text

Methods: CA 125 concentration was determined in serum samples from cubital vena and uterine vena respectively from 50 and 28 patients with uterine myoma. In the range of 0-1000 units, all assays tested correlated well with clinical findings (range of correlation coefficients 0.05 — 0.3)

Results: The CA 125 concentrations were increased in all uterine vena serum samples and were increased only in 17% of cubital serum samples.

Conclusion: We conclude that the increase of CA 125 serum level was associated with myoma necrosis, endometrial hyperplasia, intrauterine contraception usage for a long period. Moreover, the increase of CA 125 serum is an additional diagnostic test for determination of the type and time of operation.