Interferon therapy of herpes virus infection in pregnant women

Abstract

The purpose: Determination efficiensy of interferon therapy in pregnant women with herpes infection (Cytomegalovirus, Herpes simplex virus, Epstein-Barr virus).

Full Text

Methods: The research of parameters of Inlerferon status, Immune system, hormonal homeostasis, ultrasonic scanning, virusological and bacteriological investigation are led at 154 patients, treated by x-2 interferon (viferon).

Results: The investigation Indicated viferon has Interferon - stabilizing, immunomodulating, antioxidant effect and doesn’t have complications on the fetus. The reducing of the delivery channel occupation with genital herpes virus in 50% of patients have been revealed. Every newborn had no signs of herpes virus infection and specifically neurological symptoms. Increased level of Interferon-gamma from initial 2.4 to 32 IU can be related to Viferon stimulation of cytokine production. Revealed immunocorrekting effect of Viferon can be a basis for its use in mothers and newborns for treatment and prophylactics of the herpes virus infection.