Prevalence of mycoplasma hominis & ureaplasma urealyticum in pregnant of high-risk group

Abstract

Obiective: To estimate the prevalence of Mycoplasma hominis and Ureaplasma Urealyticum in pregnant of high-risk group.

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Methods: Two hundred eighty-six pregnant women of high-risk groups visiting the City Specialise Centre of the Health and Family Planning in Ekaterinburg were examined for sexually transmitted infections during the period Januarv-December 1998. C. Trachomatis, U. Urealyticum, M. hominis, herpes simplex virus, and cytomegalovirus were identified by the DNA probe assays. Laboratory diagnostics for bacterial vaginosis was carried out by the standard technique (detecting “key cells”, microscopic exam of Gram stained smear, amino-test, and pH of vaginal discharges). Candida spp. was detected by culture and by microscopic of native preparation with addition potassium hydroxide 10%. Distribution and crude significance testing were made with t tests and c² analysis (likelihood ratio and Pearson test) as appropriate.

Results: Fifty-three of the women were positive for U. Urealyticum (18.5%) and 24 for M. hominis (8.4%). U. Urealyticum. was identified as a mono infection in 10 women (18.8%). M. hominis in 2 (8.3%). We made note of high association of the given microorganisms with bacterial vaginosis: U. Urealyticum was combined in 45.3%, M. Hominis in 79.2% (p=0002). The candidiasis accompanied by U. Urealyticum in 39 women (73.6%), by M. Hominis in 15 (62,5%).

Conclusions: U. Urealyticum being more prevalent than M. Hominis (p=001). U. Urealyticum takes the 3d place alter a candidiasis and chlamydial infection, and M. hominis takes the 7th place in urogenital infection structure of high-risk group pregnant. The frequent combination M. hominis with bacterial vaginosis points to an appreciable role of genital mycoplasmas in a genesis of the pathological process. The infection by U. Urealyticum has the large bent to independent current in a kind greater enzymatic aggression of U. Urealyticum.