Significanse of laparoscopy in diagnostics of preclinical reccurence of ovarian cancer

Abstract

Objective: Ovarian cancer is the most frequently cause of death of women with malignant tumors in Russia which is considered not only with diagnostics of advanced ovarian cancer but also belated diagnostics of recurrences.

Full Text

Methods: 41 patients with ovarian cancer in clinical remission were investigated by ultrasonography (US) and CA-125. Laparoscopy was tried in cases when there are differences between features of CA-125 and US.

Results: Metastasis are observed by biopsy in 25 (86,2%) with increased level of CA-125 and in 4patients (13,8%) with negative features of US. From 12 patients with normal level of CA-125, but with positive features of US 4 (33,3%) patients have a recurrence. Results are shown in table.

	Patients	Laparoscopy positive	Laparoscopy negative
CA-125>35U/ml (US negatives)	29	25 (86,2%)	4 (13,8%)
CA-125=35U/ml (US positive)	12	8 (66,7%)	4 (33,3%)

Conclusion: For our opinion, laparoscopy may be an important criteria of early diagnosis of preclinical recurrences from patients with ovarian cancer if there are differences between levels of CA-125 and US.