The spread of HPV among young women with cervical pathology

Abstract

Objective: To study spread level of HPV 16/18 types among sexually active young women with different cervical pathology.

Full Text

Subjects and method: From October till November 1998 we examined 80 women at the age of 15 - 24 with histology and colposcopy veriflcated diagnosis cervical pathology: 69 cases (86,3%) of ectopia, 9 cases (11,2%) of CIN 1-2, 2 cases (2,5%) of endometriosis. HPV-DNA typing of cervical scrapes was done by polymerase chain reaction technique (PCR).

Results: Positive results of HPV-DNA test were in 14 cases (17,5%): 7 out of 9 with CIN 1-2 (77,8%), 7 out of 69 with ectopia (10,1%).

Discussion: The results show HPV 16/18 is widespread among sexually active young women with different cervix pathology. The presens of this type infection in patients with CIN pathology was higher then in patients with ectopia.

Conclusion: The data obtained in result could be useful for the formation of clinical groups for HPV testing and used in a second time prophylaxis of cervical cancer.