New approach to the combined treatment of endometrial cancer

Abstract

Objective: One of pathognomistic symptoms in endometrial cancer is an appearance of genital blood-streaked discharge in menopause. Some times the uterine bleeding is so profuse, accompanied by fall of hemoglobin in peripheral blood, that the performance of operative intervention is impossible.

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Methods: To obtain hemostasis, we used a method of the uterine arteries embolization. Uterine arteries embolization was performed in 64 patients with endometrial cancer at the first stage of the treatment. Autoclots, Ivalon, Gelfoam were used for occlusion.

Results: In 94% of cases it resulted in complete control of bleeding, and allowed to improve the general state of patients, to normalize blood indices. Later on, all patients were operated in the volume of the uterine extirpation with adnexia. In no cases the complications were observed connected with embolization. The operative intervention was accompanied by less blood bleeding, more ablastics. The recurrence rate in this group of patients was 5%, while in the control group it was 12%.

Conclusion: Uterine arteries embolization is a reliable method of hemostasis in patients with endometrial cancer. Uterine arteries embolization performed at the first stage of the treatment allows to realize successfully radical programs of the treatment in patients with uterine bleeding.