Primary herpes simplex virus infection in pregnancy outcomes

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Objective: The study of herpes virus infection during pregnancy is necessary because of high rate of perinatal losses and birth of babies with severe brain damages. It's well known that most severe fetal diseases take place in the first episode of genital herpetic infection during current pregnancy.

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Objective: The study of herpes virus infection during pregnancy is necessary because of high rate of perinatal losses and birth of babies with severe brain damages. It's well known that most severe fetal diseases take place in the first episode of genital herpetic infection during current pregnancy.

Methods: We analyzed pregnancy histories of 12868 patients delivered in Center in 5 years period and selected only 6 cases with the confirmed first episode of genital herpes during current pregnancy.

Results: 2 cases ofpregnancy terminated by spontaneous abortion in 21 and 26 weeks of gestation. The both fetuses had intrauterine growth retardation on 3-4 weeks and generalised herpetic infection. Morphological study of placentas showed its severe herpetic disease and decompensated form of placental insufficiency. In 4 cases - pregnancy teminated on the 32-40 weeks of gestation. Newborns died on the 7 th-40 th day of delivery. In all cases, morphological changes had been presented by local and diffuse herpetic meningoencephalitis and in one case we always found revealed porencephalic cysts.

Conclusion: So, primary herpes virus infection is rare form of infection during pregnancy, but it can lead to severe perinatal outcomes.

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作者简介

Z. Zaidieva

Research Centre of Obstetrics, Gynecology & Perinatology

编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, Moscow

V. Tioutiounnik

Research Centre of Obstetrics, Gynecology & Perinatology

Email: info@eco-vector.com
俄罗斯联邦, Moscow

N. Bubnova

Research Centre of Obstetrics, Gynecology & Perinatology

Email: info@eco-vector.com
俄罗斯联邦, Moscow

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия Эл № 77 - 6389
от 15.07.2002 г.