Preterm birth: the impact of risk factors on pregnancy outcomes

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BACKGROUND: Despite the achievements of modern obstetrics and neonatology, the problem of preterm birth remains one of the most pressing.

AIM: The aim of this study was to evaluate the influence of risk factors on the outcome of threatened preterm birth.

MATERIALS AND METHODS: This prospective cohort study included the analysis of clinical and anamnestic data of 130 patients delivered at various gestational ages. The main group comprised 68 women with preterm delivery, with the control group consisting of 62 women with timely delivery.

RESULTS: The outcome of preterm birth is adversely affected by overweight in the group of modifiable risk factors, by history of premature birth in the immediate family in the group of non-modifiable risk factors, and by a previous COVID-19, anemia and autonomic nervous system disorders in the group of potentially modifiable risk factors. The most reliable prognostic marker for the development of preterm labor was the shortening of the cervical length of less than 2.5 cm according to ultrasound.

CONCLUSIONS: The formation of risk groups based on the analysis of clinical, anamnestic, medical, and social data, as well as somatic and gynecological diseases can help avoid the development of adverse outcomes of preterm birth.

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About the authors

Regina Sh. Khalitova

Bashkir State Medical University

ORCID iD: 0000-0002-2629-2051
SPIN-code: 5533-5782


Russian Federation, 39a Gorky St., Chita, 672000

Aydar M. Ziganshin

Bashkir State Medical University

ORCID iD: 0000-0001-5474-1080
Scopus Author ID: 57196372895
ResearcherId: V-1442-2017

MD, Cand. Sci. (Med.), Assistant Professor

Russian Federation, 39a Gorky St., Chita, 672000

Irina G. Mukhametdinova

Bashkir State Medical University

ORCID iD: 0000-0003-2910-3495


Russian Federation, 39a Gorky St., Chita, 672000

Victor A. Mudrov

Chita State Medical Academy

Author for correspondence.
ORCID iD: 0000-0002-5961-5400
Scopus Author ID: 57204736023

MD, Cand. Sci. (Med.), Assistant Professor

Russian Federation, 39a Gorky St., Chita, 672000


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Supplementary files

Supplementary Files
1. Fig. 1. The structure of somatic pathology of pregnant women in the studied groups according to the International Statistical Classification of Diseases and Related Health Problems (ICD-10)

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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