Morphological and immunohistochemical especially of stilled pregnancy the first trimester

Results of histological examination showed that stilled pregnancy occurs not only when the incomplete transformation of endometrial stroma, but also in terms of its full maturation regardless of hormonal support to maintain pregnancy. With increasing gestational age, regardless of hormonal support of pregnancy complete transformation of the endometrium occurs significantly more frequently. Furthermore, role hormonal drugs is not critical for the formation of endometrial glandular system. Increased expression of estrogen receptor in the glands and stroma of endometrium during pregnancy indicate the pathology of the first phase of the menstrual cycle. The reduction of the expression of KISS1 in endometrium during pregnancy was observed by the end of the first trimester of pregnancy due to the fading of the first stage of trophoblast invasion.

stilled pregnancy, histological and immunohistochemical study, estrogen and progesterone, kisspeptin (KISS) and KISS1R receptor, vascular endothelial growth factor