Abstract
This lecture will begin by discussing the development of the fetal brain. We will look at the neuronal development with clinical correlates in all trimesters of pregnancy. Discussion of the advantages of looking at the developing fetal brain in the first trimester of pregnancy as a window into the detection of fetal anomalies will be discussed. Integration with MRI and CT imaging will be interspersed with sonographic discussion and interpretation. Common fetal CNS abnormalities will be outlined and their evolution during advancing gestation will be reviewed. Less common defects will be discussed with attention to the clues in imaging that make their diagnosis easier. The limitations of ultrasound imaging for certain CNS anomalies will be outlined in detail. This will include both fetal as well as maternal limitations. Tips and options for sonographic imaging will be interspersed within the lecture to allow the participant several options for imaging fetal anomalies with neurosonography and improving their diagnostic accuracy.