Email this article Pathomorphological features of the endometrium in patients with abnormal uterine bleeding in the presence of uterine leiomyoma
- Authors: Rumyantseva Z.S.1, Sulima A.N.1, Volotskaya N.I.1, Zyablitskaya E.Y.2, Anikin S.S.2, Glazkov I.S.3, Keshvedinova A.A.1
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Affiliations:
- Medical Academy named after S.I. Georgievsky, V.I. Vernadsky Crimean Federal University
- Medical Academy named after S. I. Georgievsky (structural unit) “V. I. Vernadsky Crimean Federal University"
- Simferopol Clinical Maternity Hospital No. 2
- Issue: Vol 69, No 6 (2020)
- Pages: 81-89
- Section: Original Research
- URL: https://journals.eco-vector.com/jowd/article/view/35220
- DOI: https://doi.org/10.17816/JOWD69681-89
- ID: 35220
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Abstract
Hypothesis/Aims of study. One of the problems discussed in the field of obstetrics and gynecology is the combined pathology of the reproductive system. Among the female reproductive system disorders associated with uterine leiomyoma, endometrial pathology prevails in the form of local inflammatory, receptor and hormonal changes. The aim of this study was to evaluate the structural features of the endometrium and its receptivity in patients with uterine leiomyoma, depending on its histological type and localization.
Study design, materials and methods. We examined 128 women with leiomyoma manifesting abnormal uterine bleeding, using clinical, instrumental and morphological methods.
Results. Combined pathological changes in the endometrium are more characteristic of submucous leiomyoma compared to intramural and subserous leiomyomas. The proliferative activity of endometrial cells in submucous leiomyoma is two or more times higher than in intramural and subserous leiomyoma. In submucous leiomyoma, cell proliferation occurs significantly more often than in other locations of myomatous nodes.
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About the authors
Zoya S. Rumyantseva
Medical Academy named after S.I. Georgievsky, V.I. Vernadsky Crimean Federal University
Email: zoyarum@inbox.ru
ORCID iD: 0000-0002-1711-021X
SPIN-code: 3480-3514
MD, PhD, Assistant Professor, Acting Head of the Department of Obstetrics, Gynecology, and Perinatology No. 1, the First Medical Faculty
Russian Federation, SimferopolAnna N. Sulima
Medical Academy named after S.I. Georgievsky, V.I. Vernadsky Crimean Federal University
Author for correspondence.
Email: gsulima@yandex.ru
ORCID iD: 0000-0002-2671-6985
SPIN-code: 2232-0458
MD, PhD, DSci (Medicine), Professor. The Department of Obstetrics, Gynecology, and Perinatology No. 1, the First Medical Faculty
Russian Federation, SimferopolNadezhda I. Volotskaya
Medical Academy named after S.I. Georgievsky, V.I. Vernadsky Crimean Federal University
Email: volotskaya.miss@yandex.ru
ORCID iD: 0000-0003-2304-659X
SPIN-code: 8174-9478
Resident. The Department of Obstetrics, Gynecology, and Perinatology No. 1, the First Medical Faculty
Russian Federation, SimferopolEvgenia Yu. Zyablitskaya
Medical Academy named after S. I. Georgievsky (structural unit) “V. I. Vernadsky Crimean Federal University"
Email: evgu79@mail.ru
ORCID iD: 0000-0001-8216-4196
SPIN-code: 2267-3643
MD, PhD, DSci (Medicine), Leading Researcher, Head of the Central Research Laboratory
Russian Federation, SimferopolSergey S. Anikin
Medical Academy named after S. I. Georgievsky (structural unit) “V. I. Vernadsky Crimean Federal University"
Email: ssssanikin@rambler.ru
ORCID iD: 0000-0001-8142-2173
SPIN-code: 5379-0703
MD, PhD, Assistant Professor. The Department of Obstetrics, Gynecology, and Perinatology No. 1, the First Medical Faculty
Russian Federation, SimferopolIlya S. Glazkov
Simferopol Clinical Maternity Hospital No. 2
Email: glazkovobstetrics@yandex.ru
ORCID iD: 0000-0002-7432-5161
SPIN-code: 4444-9078
MD, PhD, DSci (Medicine), Professor, Head
Russian Federation, SimferopolAishe A. Keshvedinova
Medical Academy named after S.I. Georgievsky, V.I. Vernadsky Crimean Federal University
Email: aishe1998@mail.ru
ORCID iD: 0000-0002-0045-2715
SPIN-code: 1577-0901
Student
Russian Federation, SimferopolReferences
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