Woman’s microbiota and pregnancy outcomes

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Abstract


A local inflammatoMicrobial invasion of amniotic cavity and subsequent infection process are the leading cause of adverse pregnancy outcomes. Intra-amniotic infection can be caused by both pathogenic and opportunistic microorga­nisms and viruses, but in the vast majority of cases intra-amniotic infection is associated with the normal microflora of different body sites – the vagina, intestines, mouth and respiratory tract. In the paper, current views about the role of infection factor in the adverse pregnancy outcomes, sources and mechanisms of intra-amniotic infection are summarized.


Eduard K. Ailamazian

D. O. Ott Research Institute of Obstetrics and Gynecology, RAMS

Author for correspondence.
Email: iagmail@ott.ru

Russian Federation Professor, Academician of RAS, Director

Elena V. Shipitsyna

D. O. Ott Research Institute of Obstetrics and Gynecology, RAMS

Email: iagmail@ott.ru

Russian Federation PhD, Senior Researcher, Laboratory of Microbiology

Alevtina M. Savicheva

D. O. Ott Research Institute of Obstetrics and Gynecology, RAMS

Email: savitcheva@mail.ru

Russian Federation MD, Professor, Head of Laboratory of Microbiology

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