The role of papillomavirus and herpesvirus infections in the origins and genesis of genital endometriosis. A literature review

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Abstract

Endometriosis is a chronic multifactorial disease that affects one in ten women of reproductive age. Genetic, endocrine and immunological factors play an important role in the pathogenesis of endometriosis. In recent years, an increasing number of studies have been devoted to the role of vaginal microbiota in the pathogenesis of endometriosis. However, the role of viral infections, such as papillomavirus and herpesvirus infections, in the development of the disease has not been sufficiently studied. The review highlights current ideas about the role of human papillomavirus and herpesvirus infections in the genesis of endometriosis. The data obtained have convinced us of the need to further search for new relationships between papillomavirus and herpesvirus infections, microbiota of reproductive organs and pathogenesis of such a complicated disease as endometriosis.

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About the authors

Aigul M. Khanova

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Author for correspondence.
Email: musannifovna@gmail.com
ORCID iD: 0000-0002-6438-5195
Russian Federation, Saint Petersburg

Armine R. Khachaturian

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: armine2709@mail.ru
ORCID iD: 0000-0003-2141-6307
SPIN-code: 2691-3910

MD, Cand. Sci. (Med.)

Saint Barthélemy, Saint Petersburg

Tatiana A. Khusnutdinova

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: husnutdinovat@yandex.ru
ORCID iD: 0000-0002-2742-2655
SPIN-code: 9533-9754

MD, Cand. Sci. (Med.)

Russian Federation, Saint Petersburg

Alevtina M. Savicheva

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: savitcheva@mail.ru
ORCID iD: 0000-0003-3870-5930
SPIN-code: 8007-2630

MD, Dr. Sci. (Med.), Professor, Honored Worker of Science of the Russian Federation

Russian Federation, Saint Petersburg

Maria I. Yarmolinskaya

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: m.yarmolinskaya@gmail.com
ORCID iD: 0000-0002-6551-4147
SPIN-code: 3686-3605

MD, Dr. Sci. (Med.), Professor of the Russian Academy of Sciences

Russian Federation, Saint Petersburg

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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