Bilateral anogenital mammary-like glands lactating in the puerperium. A clinical case

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Abstract

This article presents a rare case of a woman having bilateral anogenital mammary-like glands, lactating in the postpartum period, and a surgical solution to the problem. The histology of the removed tissue corresponded to the morphology of the breast during lactation. No complications occurred after surgery.

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About the authors

Natalya V. Kulagina

North-Western State Medical University named after I.I. Mechnikov

Email: dr.kulagina@mail.ru
ORCID iD: 0000-0002-9683-5963
SPIN-code: 8348-8592
Scopus Author ID: 57194349425

MD, Dr. Sci. (Med.), Assistant Professor

Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015

Dmitry S. Sudakov

North-Western State Medical University named after I.I. Mechnikov; The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Author for correspondence.
Email: suddakovv@yandex.ru
ORCID iD: 0000-0002-5270-0397
SPIN-code: 6189-8705
Scopus Author ID: 57214315137

MD, Cand. Sci. (Med.)

Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015; 3 Mendeleevskaya Line, Saint Petersburg, 199034

Mikhail S. Dobrovolsky

Women’s Consultation No. 44

Email: dr-do@rambler.ru

MD

Russian Federation, Saint Petersburg

References

  1. Mayer RB, Enengl S, Witzany H, et al. Postpartum galactostasis of the vulva in a case of bilateral lactating ectopic breast tissue. Obstet Gynecol. 2019;134(1):138–140. doi: 10.1097/AOG.0000000000003313
  2. Lee E-S, Kim I. Multiple vulvar lactating adenomas. Obstet Gynecol. 2011;118(2):478–480. doi: 10.1097/AOG.0b013e31821ecaa2
  3. Swanson LA, Sharain RF, Gruenberg JM, et al. Ectopic breast tissue of the vulva in a post-partum woman. Int J Women’s Dermatol. 2020;6(3):236–237. doi: 10.1016/j.ijwd.2020.03.036
  4. Sahu S, Husain M, Sachan P. Bilateral accessory breast. The Internet Journal of Surgery. 2007;17(2). Available from: https://print.ispub.com/api/0/ispub-article/6741
  5. Al-Badawi IA, Al-Sabban M. Unilateral ectopic mammary-like tissue in the vulva. J Obstet Gynaecol Can. 2014;36(11):951. doi: 10.1016/S1701-2163(15)30403-5
  6. Ahmed S, Ding C, Shelat VG. Ectopic breast tissue in the vulva masquerading as an abscess. Singapore Med J. 2020;61(5):281–282. doi: 10.11622/smedj.2018121
  7. Kajava Y. The proportions of supernumerary nipples in the Finnish population. Duodecim. 1915;1:143–170
  8. Surcel E, Koljonen V. Kajava Classification: the person and the research. Aesthetic Plast Surg. 2023;47(5):2177–2178. doi: 10.1007/s00266-023-03451-7
  9. Sibirskaya EV, Argun MZ, Li K, et al. Developmental anomalies of mammary glands. Difficult Patient. 2021;19(6):40–44. EDN: CWUAOR doi: 10.224412/2074-1005-2021-6-40-44
  10. Javed A, Lteif A. Development of the human breast. Semin Plast Surg. 2013;27(1):5–12. doi: 10.1055/s-0033-1343989
  11. Mareti E, Vatopoulou A, Spyropoulou GA, et al. Breast disorders in adolescence: a review of the literature. Breast Care. 2021;16(2):149–155. doi: 10.1159/000511924
  12. Pieh-Holder KL. Lactational ectopic breast tissue of the vulva: case report and brief historical review. Breastfeed Med. 2013;8:223–225. doi: 10.1089/bfm.2012.0128
  13. Saribekyan EK, Efanov VV, Shirokikh IM, et al. Accessory breast. Clinical case. Research’n Practical Medicine Journal. 2015;2(4):77–81. EDN: SYQXRM doi: 10.17709/2409-2231-2015-2-4-77-81
  14. Song Y, Zhang J, Liu Z, et al. Periclitoral accessory breast tissue in a lactating woman: a case report. Medicine. 2018;97(43). doi: 10.1097/MD.0000000000012936.
  15. Godoy-Gijón E, Yuste-Chaves M, Santos-Briz A, et al. Accessory breast on the vulva. Actas Dermosifiliogr. 2012;103(3):229–232. doi: 10.1016/j.ad.2011.02.015
  16. Tow SH, Shanmugaratnam K. Supernumerary mammary gland in the vulva. Br Med J. 1962; 2(5314):1234–1236. doi: 10.1136/bmj.2.5314.1234
  17. Hartung E. Ueber einen fall von mamma accessoria. Inaugural — Abhandlung der medicinischen Facultät zu Erlangen. Erlangen, 1872 (In Ger.) [cited 12.02.2024]. Available from: https://archive.org/details/b22300387/page/12/mode/thumb
  18. Duvvur S, Sotres M, Lingam K, et al. Ectopic breast tissue of the vulva. J Obstet Gynaecol. 2007l;27(5):530–531. doi: 10.1080/01443610701467333
  19. Mikhael S, Nilsson W, Patel K, et al. Ectopic breast tissue of the vulva in a postmenopausal woman. Case Rep Obstet Gynecol. 2017;2017. doi: 10.1155/2017/7581750
  20. Lev-Cohain N, Kapur P, Pedrosa I. Vulvar fibroadenoma with lactational changes in ectopic breast tissue. Case Rep Obstet Gynecol. 2013;2013. doi: 10.1155/2013/924902
  21. Levin N, Diener RL. Bilateral ectopic breast of the vulva. Report of a case. Obstet Gynecol. 1968;32(2):274–276.
  22. Reeves KO, Kaufman RH. Vulvar ectopic breast tissue mimicking periclitoral abscess. Am J Obstet Gynecol. 1980;137(4):509–511. doi: 10.1016/0002-9378(80)91138-2
  23. Kapila K, Al-Rabah NA, Junaid TA. Ectopic breast tissue on the vulva diagnosed by fine needle aspiration. Acta Cytol. 1998;42(6):1480–1481. doi: 10.1159/000332190
  24. Basu S, Bag T, Saha KS, et al. Accessory breast in the perineum. Trop Doct. 2003;33(4):245. doi: 10.1177/004947550303300420
  25. Bardsley M, Petterson C. Ectopic breast tissue presenting as a persistent vulval cyst. Aust N Z J Obstet Gynaecol. 2004;44(2):166–167. doi: 10.1111/j.1479-828X.2004.00201.x
  26. Pathak S, Preston J. A rare case of multiple accessory breast tissue in the axillae, lower abdomen and vulval areas. J Obstet Gynaecol. 2007;27(5):531–533. doi: 10.1080/01443610701467473
  27. Larson S, Yang S, Chacko-Stacey A, et al. Self-resolving vulvar breast tissue arising in the post-partum setting: a case report and review of literature. J Hum Lact. 2020;36(2):348–351. doi: 10.1177/0890334419849593
  28. Baradwan S, Wadi KA. Unilateral ectopic breast tissue on vulva in postpartum woman: a case report. Medicine. 2018;97(6). doi: 10.1097/MD.0000000000009887
  29. Lightman SL, Windle RJ, Wood SA, et al. Peripartum plasticity within the hypothalamo–pituitary–adrenal axis. Prog Brain Res. 2001;133:111–129. doi: 10.1016/s0079-6123(01)33009-1
  30. Neville MC, Morton J. Physiology and endocrine changes underlying human lactogenesis II. J Nutr. 2001;131(11):3005S–3008S. doi: 10.1093/jn/131.11.3005S
  31. Tomer L, Toschi N, Nava G, et al. Increased hypothalamic expression of prolactin in lactation involvement in behavioral and neuroendocrine stress responses. Eur J Neurosci. 2002;15(8):1381–1389. doi: 10.1046/j.1460-9568.2002.01965.x
  32. Budanov PV. Physiology and pathology of lactation. Eurasian Union of Scientists. 2019;9–3:20–33. EDN: DPQJML doi: 10.31618/ESU.2413-9335.2019.3.66.311
  33. Gugliotta P, Fibbi ML, Fessia L, et al. Lactating supernumerary mammary gland tissue in the vulva. Appl Pathol. 1983;1(2):61–65.
  34. Dhaoui A, Nfoussi H, Kchir N, et al. Vulvar lactating adenoma associated to a fibroadenoma: common neoplasms in an uncommon site. Pan Afr Med J. 2012;13:47.
  35. Van der Putte SC. Mammary-like glands of the vulva and their disorders. Int J Gynecol Pathol. 1994;13(2):150–160. doi: 10.1097/00004347-199404000-00009
  36. Thiryayi SA, Rouzbahman M, Ghazarian D. A case of postpartum anogenital mammary-like gland tumor with focal lactational features: a nomenclature issue. Case Rep Pathol. 2019;2019. doi: 10.1155/2019/6703248.
  37. Konstantinova AM, Belousova IE, Kacerovska D, et al. Morphology of anogenital mammary-like glands. Vestnik SPbSU. Medicine. 2017;12(1):83–93. EDN: ZDOTAX doi: 10.21638/11701/spbu11.2017.107
  38. Van der Putte SC. Anogenital “sweat” glands. Histology and pathology of a gland that may mimic mammary glands. Am J Dermatopathol. 1991;13(6):557–567.
  39. Konstantinova AM. Histological concept and classification of formations of anogenital mammary-like glands [dissertation]. Saint Petersburg; 2021. (In Russ.)
  40. Willman J, Golitz L, Fitzpatrick J. Vulvar clear cells of Toker: precursors of extramammary Paget’s disease. Am J Dermatopathol. 2005;27(3):185–188. doi: 10.1097/01.dad.0000158291.20440.13
  41. McClain CM, Deavers M, Sauls CD, et al. Hidradenoma papilliferum associated with pregnancy: a case report. J Cutaneous Pathology. 2015;42(12):983–986. doi: 10.1111/cup.12586
  42. O’Hara M, Page D. Adenomas of the breast and ectopic breast under lactational influences. Hum Pathol. 1985;16(7):707–712. doi: 10.1016/s0046-8177(85)80156-8
  43. Kurashige Y, Kishida K, Kurashige K, et al. Hidradenoma papilliferum of the vulva in association with an anogenital mammary-like gland. J Dermatol. 2014;41(5):411–413. doi: 10.1111/1346-8138.12433
  44. Sanchita D, Ruchi J. Unilateral Ectopic breast tissue in the vulva — a diagnostic dilemma. J Midlife Health. 2023;14(1):46–48. doi: 10.4103/jmh.jmh_209_22
  45. Mansouri G, Alkatout I, Iranpour M, et al. Unexpected presentation of accessory breast: vulvar accessory breast tissue: a case report // J Med Case Rep. 2023;17(1):189. doi: 10.1186/s13256-023-03930-0
  46. Buitrago-Flechas SM, Barrera-Latorre SJ, Morante-Caicedo C. Ectopic mammary tissue in vulva: case report and systematic literature review. Rev Colomb Obstet Ginecol. 2021;72(3):271–290. doi: 10.18597/rcog.3593
  47. Ardell S., Udayasankar V. Ectopic breast tissue in the vulva in pregnancy. J Obstet Gynaecol Can. 2021;43(5):541. doi: 10.1016/j.jogc.2019.09.026
  48. Zhang L, Yao XL, Zhu X, et al. Ectopic breast tissue of the vulva. Pol J Pathol. 2023;74(2):141–143. doi: 10.5114/pjp.2023.128787
  49. Wagner IJ, Damitz LA, Carey E, et al. Bilateral accessory breast tissue of the vulva: a case report introducing a novel labiaplasty technique. Ann Plast Surg. 2013;70(5):549–552. doi: 10.1097/SAP.0b013e31827ead39
  50. Kazakov DV, Spagnolo DV, Kacerovska D, et al. Lesions of anogenital mammary-like glands: an update. Adv Anat Pathol. 2011;18(1):1–28. doi: 10.1097/PAP.0b013e318202eba5
  51. Scarabin C, Koskas M, Bornes M, et al. Gigantomastia and vulvar lactating adenoma in a patient with myasthenia during pregnancy. Am J Obstet Gynecol. 2010;203(4):e5–8. doi: 10.1016/j.ajog.2010.07.001

Supplementary files

Supplementary Files
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1. JATS XML
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2. Fig. 1. Secretory changes in lactating adenoma [34]. Hematoxylin and eosin staining, zoom ×400

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3. Fig. 2. Glandular cysts and apocrine secretion [34]. Hematoxylin and eosin staining, zoom ×40

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4. Fig. 3. Ectopic breast tissue in the vulva [34]. Hematoxylin and eosin staining, zoom ×200

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5. Fig. 4. Anogenital mammary-like gland [39]. Hematoxylin and eosin staining, zoom ×10

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6. Fig. 5. Bilateral tumors of the labia majora, 7 days after cesarean section

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7. Fig. 6. Cystic structure of tumors of the labia majora in ultrasound examination, 8 days after delivery

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8. Fig. 7. Ducts inside tumors of the labia majora in ultrasound examination, 8 days after delivery

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9. Fig. 8. Cytological examination of tumor secretion: positive reaction, fat. Sudan III staining, zoom ×100

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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